PET/MRI观察朗格汉斯细胞组织细胞增生症

目的 观察朗格汉斯细胞组织细胞增生症（LCH）的¹⁸F-FDG PET/MRI表现。方法 回顾性分析11例经病理学证实的LCH患者PET/MRI所示各系统病灶部位、数目、形态及最大标准摄取值（SUV_max）。结果 11例LCH中，8例为症状或影像学未缓解、3例为影像学缓解病例；其中7例累及全身多系统，4例仅累及骨骼系统或垂体，临床表现与病变累及范围相关。8例未缓解LCH中，PET/MRI共检出38个病灶，多表现为不同程度FDG摄取增高，SUV_max为1.23~13.00。结论 LCH累及范围多较广，PET/MRI中病变多呈不同程度FDG摄取增高。

PET/MRI observation on Langerhans cell histiocytosis

Objective To observe ¹⁸F-FDG PET/MRI manifestations of systemic multisystem Langerhans cell histiocytosis (LCH). Methods PET/MRI findings of 11 patients with various systems LCH confirmed by pathology were observed, and the location, number, morphology and the maximum standard uptake value (SUV_max) of lesions were evaluated. Results Among 11 patients of LCH, 8 were symptoms or imaging not relieved LCH, the rest 3 were imaging remission LCH cases. LCH involved multiple systems throughout the body in 7 cases, while involved only the skeletal system or pituitary in the rest 4 cases, and the clinical manifestations were related to the extent of lesion involvement. Among 8 cases without remission, PET/MRI showed a total of 38 lesions, most manifested as increased FDG uptake in varying degrees, with SUV_max ranging from 1.23 to 13.00. Conclusion LCH tented to involve multiple systems throughout the body, and most lesions manifested as increased FDG uptake in varying degrees on PET/MRI.