| 复方茵黄解毒汤质量标准研究 |
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| 引用本文： | 杨芳,许重远,李亦蕾,彭康.复方茵黄解毒汤质量标准研究[J].中国药房,2008,19(9):696-698. |
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| 作者姓名： | 杨芳 许重远 李亦蕾 彭康 |
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| 作者单位： | 1. 南方医科大学南方医院药学部,广州市,510515
2. 南方医科大学中医药学院,广州市,510515 |
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| 摘 要： | 目的:建立复方茵黄解毒汤的质量标准。方法:采用薄层色谱(TLC)法对处方中蒲公英、大黄、黄柏进行定性鉴别;采用高效液相色谱(HPLC)法测定咖啡酸和阿魏酸的含量。结果:TLC中蒲公英、大黄、黄柏斑点清晰;咖啡酸与阿魏酸的检测浓度分别在8～40μg·mL-1(r=0·9997)、8～40μg·mL-1(r=0·9995)范围内与各自峰面积积分值呈良好的线性关系;二者平均回收率分别为99·29%与99·38%,RSD分别为0·81%与0·65%(n=6)。结论:所建标准可用于本品的质量控制。
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| 关 键 词： | 复方茵黄解毒汤 质量标准 薄层色谱法 高效液相色谱法 |
| 文章编号： | 1001-0408（2008）09-0696-03 |
| 收稿时间： | 2007-07-29 |
| 修稿时间： | 2007-11-05 |
Quality Standards of Compound Yinhuang Detoxication Decoction |
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| YANG Fang,XU Zhong-yuan,LI Yi-lei,PENG Kang.Quality Standards of Compound Yinhuang Detoxication Decoction[J].China Pharmacy,2008,19(9):696-698. |
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| Authors: | YANG Fang XU Zhong-yuan LI Yi-lei PENG Kang |
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| Abstract: | OBJECTIVE:To establish the quality standards for Compound Yinhuang detoxication decoction.METHODS:Herba Taraxaci,Radix Et Rhizoma Rhei,and Cortex Phellodendri in the formula were identified qualitatively by TLC;the contents of Caffeic acid and FeruLic acid were determined by HPLC.RESULTS:The TLC spots of Herba Taraxaci,Radix Et Rhizoma Rhei,and Cortex Phellodendri were all clear.The linear range of Caffeic acid was 8～40 μg·mL-1(r=0.999 7) versus 8～40 μg·mL-1(r=0.999 5) of Ferulic acid.The average recoveries were 99.29% and 99.38% with RSD at 0.81% and 0.65%(n=6),respectively.CONCLUSION:The established standards can be used for the quality control of Compound Yinhuang detoxication decoction. |
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| Keywords: | Compound Yinhuang detoxication decoction Quality standards TLC HPLC |
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