Narcotrend监测下氟比洛芬脂复合丙泊酚麻醉用于无痛人流术的理想麻醉深度探讨

目的：探讨Narcotrend监测下无痛人流治疗的理想麻醉深度.方法：300例择期在丙泊酚静脉麻醉下行无痛人流治疗的门诊患者,20~36岁,ASAⅠ~Ⅱ级,随机均分为3组;A组（Narcotrend指数即NI,维持在D0）,B组（NI维持在D2）,C组（NI维持在E1）.在Narcotrend监测下靶控输注丙泊酚进行诱导,待患者NI值分别降至设定值2 min后开始无痛人流治疗.观察并记录患者的血流动力学变化,不良反应,苏醒时间和丙泊酚用量.结果：B组和C组高血压、心动过速、体动的发生率显著低于A组（P〈0.05）,C组低血压和心动过缓的发生率显著高于A组和B组（P〈0.05）,B组呼吸抑制的发生率显著低于A组和C组（P〈0.05）;B组丙泊酚用量和清醒时间显著小于A组和C组（P〈0.05）.结论：Narcotrend监测下患者靶控输注丙泊酚行无痛人流治疗检查的理想麻醉深度为D2,此麻醉深度可减少丙泊酚用量,减少不良反应及缩短麻醉复苏时间.

Ideal depth of anesthesia in painless induced abortion treatment with flurbiprofen axetil and propofol intravenous anesthesia under Narcotrend monitoring

Objective：To study ideal depth of anesthesia under Narcotrend monitoring in painless induced abortion treat- ment. Methods ：300 patients aged 20 ~ 36, ASA I - II , performed painless induced abortion under anesthesia with propofol intravenous, are divided into three groups randomly. Group A （Narcotrend index NI, maintained at the D0） and group B （NI at D2）, group C （NI at E1 ）. Under Narcotrend monitoring, the infusion of propofol through control of tar- get on inducing. Not until 2 rain when NI value was reduced to the set point, did the painless induced abortion start. The patients＇hemodynamic changes, adverse reactions, awakening time and the dosage of propnfol were observed and recor- ded. Results：The incidence of hypertension, tachycardia, body moving in group B and group C significantly lower than that of group A （P 〈 0.05 ）. The incidence of hypotension and bradycardia in group C were significantly higher than that of group A and group B （ P 〈 0.05 ）. The incidence of respiratory depression in group B was significantly lower than that of group A and group C （P 〈 0.05）. The dosage of propofol and awakening time in group B significantly less than that of group A and group C （P 〈 0. 05）. Conclusion ： The ideal anesthesia depth of this procedure is D2, which results in re- duced dosage of propofol, adverse reaction and anesthesia recovery time.