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狗针麻胃大部切除术中胃壁APUD细胞5-HT荧光组织化学变化
引用本文:彭俊云,周舒,郑超强.狗针麻胃大部切除术中胃壁APUD细胞5-HT荧光组织化学变化[J].针刺研究,1980(3).
作者姓名:彭俊云  周舒  郑超强
作者单位:中国医学科学院基础医学研究所针麻原理研究室 (彭俊云,周舒),中国医学科学院基础医学研究所针麻原理研究室(郑超强)
摘    要:<正> 我室曾经观察到针麻胃大部切除术病人针麻效果好时血浆游离5-羟色胺(5-HT)水平较低,血小板向血浆中释放5-HT的量较少最近,在狗的针麻胃大部切除实验模型上还观察到针麻效果好时,血中5-HT 总量升高率也较针麻效果差者为低。


FLUOROHISTOCHEMICAL CHANGES OF SEROTONIN IN APUD-CELLS OF THE STOMACH WALL OF DOGS DURING SUBTOTAL GASTRECTOMY UNDER ACUPUNCTURE ANESTHESIA
Abstract:The fluorobistochemical changes of 5-HT in amine precurssor uptake and decarboxylation(APUD)cells of the gastric mucous membrane removed from dogs during subtotal gastrectomy under acupunc-ture anesthesia,Nembutal anesthesia,as well as control group without anesthesia were observed byglyoxylic acid induced fluorescence method.The results showed that the 5-HT fluorescent intensity in APUD cells of the stomach wall wasclosely related to the effect of acupuncture anesthesia.The amount of fluorescent cells and the fluore-scent intensity were both increased in dogs with excellent acupuncture anesthetic effect(grade Ⅰ)anddecreased in those with poor effect.Further,it was also observed that in grade I cases there were more fluorescent noradrenergic ter-minals in the vicinity of the APUD-cells containing more 5-HT.These results support the authors assumption that acupuncture might bring about a relative steadystate of the sympathetic nerve
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