| N-[4-(间甲基苯甲酰基哌嗪)乙酰基]-N-甲基-3-(1-萘氧基)-3-(2-噻吩基)-丙胺的合成 |
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| 引用本文： | 刘敏,章文军,赵姣,刘东.N-[4-(间甲基苯甲酰基哌嗪)乙酰基]-N-甲基-3-(1-萘氧基)-3-(2-噻吩基)-丙胺的合成[J].化学试剂,2009,31(12). |
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| 作者姓名： | 刘敏 章文军 赵姣 刘东 |
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| 作者单位： | 河北工业大学,化工学院,天津,300130 |
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| 基金项目： | 河北省自然科学基金资助项目 |
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| 摘 要： | 以N-甲基-3-(1-萘氧基)-3-(2-噻吩基)-丙胺(Duloxetine)为原料,合成了标题化合物.中间体和产物的结构经 ~1HNMR、IR和质谱表征.
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| 关 键 词： | N-甲基-3-(1-萘氧基)-3-(2-噻吩基)-丙胺 N-[4-(间基苯甲酰基哌嗪)乙酰基]-N-甲基-3-(1-萘氧基)-3-(2-噻吩基)-丙胺 抗抑郁药 合成 |
Synthesis of N-methyl-2-(4-(3-methylbenzoyl)piperazin-1-yl)-N-(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl)acetamide |
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| LIU Min,ZHANG Wen-jun,ZHAO Jiao,LIU Dong.Synthesis of N-methyl-2-(4-(3-methylbenzoyl)piperazin-1-yl)-N-(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl)acetamide[J].Chemical Reagents,2009,31(12). |
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| Authors: | LIU Min ZHANG Wen-jun ZHAO Jiao LIU Dong |
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| Abstract: | A new compound N-methyl-2-(4-(3-methylbenzoyl)piperazin-1-yl)-N-(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl) propyl)acetamide was synthesized from the starting material duloxetine.The intermediates and the product were characterized by ~1HNMR,IR and MS. |
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| Keywords: | duloxetine N-methyl-2-(4-(3-methylbenzoyl)piperazin-1-yl)-N-(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl) propyl)acetamide antidepressant synthesis |
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