| 正常青年人群脑磁共振扩散张量成像的定量研究 |
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| 引用本文： | 董大伟,梁英魁,李少武,孙波,.正常青年人群脑磁共振扩散张量成像的定量研究[J].放射学实践,2009,24(6):591-594. |
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| 作者姓名： | 董大伟 梁英魁 李少武 孙波 |
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| 作者单位： | 1. 首都医科大学附属北京天坛医院神经放射中心,北京,100050
2. 中国人民解放军海军总医院PET中心 |
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| 摘 要： | 目的:运用扩散张量成像(DTI)方法研究正常青年人群不同脑组织及解剖部位的各向异性特点.方法:对40名正常青年人群行DTI成像,分析其表面扩散系数(ADC)图及各向异性分数(FA)图的特点,并对不同脑组织进行ADC及FA值的定量分析,通过统计学分析得出其扩散和各向异性特点.结果:扩散系数ADC不能区分脑灰质与脑白质(ADC分别为807.78±90.29,775.79±115.31×10-6mm2/s,P=0.098).而脑脊液、脑灰质与脑白质间的FA值间差异均具有显著性意义(P<0.05).不同解剖部位的脑白质间具有显著不同的各向异性(P<0.05).胼胝体压部的各向异性程度最高(0.73±0.09),其次为胼胝体膝部与内囊后肢(0.68±0.05,0.67±0.06),半卵圆中心与枕钳最低(0.53±0.09,0.53±0.09).脑灰质中以背侧丘脑具有最高的各向异性(0.31±0.04).结论:FA可准确定量正常青年人群不同脑组织的扩散特点,DTI可清晰显示脑内白质的方向及走行.
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| 关 键 词： | 磁共振成像 青少年 脑 |
Quantitative Study of Normal Young Adult Brain by Using Magnetic Resonance Diffusion Tensor Imaging |
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| DONG Da-wei,LIANG Ying-kuai,LI Shao-wu,et al..Quantitative Study of Normal Young Adult Brain by Using Magnetic Resonance Diffusion Tensor Imaging[J].Radiologic Practice,2009,24(6):591-594. |
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| Authors: | DONG Da-wei LIANG Ying-kuai LI Shao-wu |
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| Affiliation: | DONG Da-wei,LIANG Ying-kuai,LI Shao-wu,et al.Department of Neuroradiology,Beijing Tiantan Hospital of the Capital University of Medical Science,Beijing 100050,P.R.China |
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| Abstract: | Objective:To study the diffusion anisotropic features of different tissues and structures of normal young adults brain by using magnetic resonance diffusion tensor imaging.Methods:Forty normal young adults were examined by magnetic resonance diffusion tensor imaging (DTI).The signal features of different brain structures on both apparent diffusion coefficient (ADC) and fractional anisotropy (FA) maps were analyzed.The ADC and FA values were measured,and the results were analyzed statistically.Results:There ... |
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| Keywords: | Magnetic resonance imaging Adolescent Brain |
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