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人工流产后不孕患者抗精子抗体监测
引用本文:杨石强,常笑雪,黄鹂,温晓华,赵荣坡,张鑫.人工流产后不孕患者抗精子抗体监测[J].郑州大学学报(医学版),1997(2).
作者姓名:杨石强  常笑雪  黄鹂  温晓华  赵荣坡  张鑫
作者单位:洛阳医学高等专科学校组织学与胚胎学教研室
摘    要:采用酶联免疫吸附试验(ELISA),对78例因人工流产后所引起的不孕症、140例非人工流产不孕症以及28例正常已婚育龄妇女进行血清抗精子抗体检测。结果:人工流产后不孕组、非人工流产不孕组及正常组抗精子抗体的阳性率分别为33.33%,15.71%,3.57%。人工流产后不孕组血清中抗精子抗体的阳性率显著高于非人工流产不孕组和正常已婚育龄妇女(P<0.05)。提示:由人工流产后所引起的不孕症,在某些方面可能与免疫因素有关。子宫内膜的破损和炎症可能是抗精子抗体产生的一个重要诱因。

关 键 词:人工流产  不孕  抗精子抗体

Determination of antisperm antibody in patients with in fertility after induced abortion
Yang Shiqiang,Chang Xiaoxue,Huang Li,Wen Xiaohua,Zhan Rongpo,Zhang Xin Division of Histology and Embryology,Luoyang Medical College,Luoyang.Determination of antisperm antibody in patients with in fertility after induced abortion[J].Journal of Zhengzhou University: Med Sci,1997(2).
Authors:Yang Shiqiang  Chang Xiaoxue  Huang Li  Wen Xiaohua  Zhan Rongpo  Zhang Xin Division of Histology and Embryology  Luoyang Medical College  Luoyang
Affiliation:Yang Shiqiang,Chang Xiaoxue,Huang Li,Wen Xiaohua,Zhan Rongpo,Zhang Xin Division of Histology and Embryology,Luoyang Medical College,Luoyang 471003
Abstract:Enzyme linked immunosorbent assays (ELISA) were done to test serum antisperm antibody (AsAb) in 78 cases of infertility caused by induced abortion,140 cases of non induced abortion infertility and 28normal married women of child bearing age.The results showed that the positive rate were 33.33%, 15.71% and 3.57% respectively.The AsAb positive rate in the serum of those whose infertility was caused by induced abortion was significantly higher than that of those whose infertility was not caused by induced abortion and the normal group ( P <0.05).It is noted that certain factors of infertility caused by induced abortion may be related to immunity.The damage and inflammation in the endometrium may be the main incentive to the formation of antisperm antibody.
Keywords:induced  abortion  infertility  antisperm  antibody
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