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桑黄多糖分散片的制备及质量控制
引用本文:王小芳,戈延茹,夏国华,戚雪勇,傅海珍.桑黄多糖分散片的制备及质量控制[J].江苏大学学报(医学版),2011,21(1):76-79,92.
作者姓名:王小芳  戈延茹  夏国华  戚雪勇  傅海珍
作者单位:江苏大学药学院,江苏,镇江,212013
基金项目:江苏大学高级人才引进专项资助项目
摘    要:目的:研究确定桑黄多糖分散片的处方,并对其进行质量研究.方法:以崩解时限为主要指标,采用正交法对桑黄多糖分散片的辅料进行筛选,并对其质量控制进行研究.结果:采用20%低取代羟丙基纤维素为崩解剂,50%微晶纤维素为填充剂,50%的乙醇溶液为粘合剂,硬脂酸镁为润滑剂,湿法制粒压片.制备的分散片每片含桑黄多糖50 mg,崩解...

关 键 词:桑黄多糖  分散片  质量控制

Preparation and quality control of dispersible tablets of polysachari-des isolated from Phellinus linteus
WANG Xiao-fang,GE Yan-ru,XIA Guo-hua,QI Xue-yong,FU Hai-zhen.Preparation and quality control of dispersible tablets of polysachari-des isolated from Phellinus linteus[J].Journal of Jiangsu University Medicine Edition,2011,21(1):76-79,92.
Authors:WANG Xiao-fang  GE Yan-ru  XIA Guo-hua  QI Xue-yong  FU Hai-zhen
Affiliation:WANG Xiao-fang,GE Yan-ru,XIA Guo-hua,QI Xue-yong,FU Hai-zhen(School of Pharmacy,Jiangsu University,Zhenjiang Jiangsu 212013,China)
Abstract:Objective: To study the preparation and quality control of dispersible tablets of polysaccharides isolated from Phellinus linteus.Methods: Under the control of indicators such as the disintergration time,the formulation of Phellinus linteus polysaccharides dispersible tablets was optimized by an orthogonal design.The quality control method was evaluated.Results: The optional formulation was consisted of 50 mg polysaccharides from Phellinus linteus,20% low substituted hydroxypropyl cellulose(L-HPC) as disint...
Keywords:Phellinus linteus polysaccharides  dispersible tablets  quality control  
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