深圳地区高层管理人员脂肪肝危险因素分析

目的探讨深圳市高层管理人员脂肪肝危险因素。方法对深圳市企事业单位高层管理人员1515例体检者进行身高、体重、腰围、臀围、腹部B超、血脂等检测,并按腰臀比值、体质指数、高脂血症进行分层分析各组危险因素与脂肪肝的相关性。结果受检者脂肪肝患病率为21.19%（男性：28.09%,女性：8.84%）,中心性肥胖组（按WHR分型）和外周肥胖组（按BMI分型）的脂肪肝的检出率明显高于正常体型和正常体重组（P〈0.01）。中心性肥胖的脂肪肝患病率明显高于外周肥胖（P〈0.01）。中心性肥胖与外周肥胖都与脂肪肝的患病率呈正相关（P〈0.01）。结论深圳地区高层管理人员脂肪肝患病率较高,肥胖、高脂血症是导致脂肪肝的独立危险因素,中心性肥胖比外周型肥胖危险性更大。腰臀比值与体质指数都可作为脂肪肝的危险预测因素,腰臀比值比体质指数特异性更高,两者结合进行可明显提高脂肪肝风险预测的特异性和敏感性。

The risk factors of fatty liver disease in high socio-economic class population of Shenzhen

Objective To explore the risk factors of fatty liver disease in people from middle to high socioeconomic class in Shenzhen.Methods 1515 managers in Shenzhen enterprises from Jan 2008 to Jun 2008 were divided into groups by WHR and BMI,then checked up with height,weight,waist circumference,hip circumference,liver ultrasonic and blood lipid.The relationship and epidemiological characteristics between each group and obesity,hyperlipideamia,FLD were analyzed.Results The prevalence of obesity is 27.6%,overweight is 21.4%,and abdominal adiposity is 24.8%.The prevalence of hyperlipideamia is 55.25%（male：63.89%,female：39.78%）,fatty liver disease is 21.19%（male：28.09%,female：8.84%）.Hyperlipideamia and FLD in abdominal adiposity group（were divided by WHR） and overall obesity group（were divided by BMI） were examined more than normal weight group（p〈0.01）.Abdominal adiposity have a significant with the prevalence of hyperlipideamia and FLD than overall obesity（p〈0.01）.Both abdominal adiposity and overall obesity were found positively related with hyperlipideamia and FLD（p〈0.01）.Conclusion The prevalence of obesity and FLD in people from middle to high socio-economic class in Shenzhen is lower than general population.Obesity and hyperlipideamia could be used as effective indexes to predict the occurrence of FLD.Abdominal adiposity is a stronger risk factor compare with overall obesity.The specificity and sensitivity of diagnosing FLD are significantly higher by using WHR than by BMI.