性乱个体血清抗-HCV的调查

用第二代酶免疫试剂对208位性乱个体进行血清丙型肝炎病毒抗体(抗-HCV)的检测,107位献血员作对照,并结合部分乙肝病毒血清标志(HBVM)进行分析和比较。结果抗-HCV总阳性率为8.65％(18/208),伴有性病者阳性率12.73%(14/110),不伴性病者4.1％(4/98),对照组抗-HCV阳性率1.87％(2/107)。18例抗-HCV阳性血清中检出乙肝病毒表面抗原(HBsAg)及核心抗体(抗-HBc)13例(72.2％),未发现抗-HCV阳性与年龄、性别相关。结果提示,性乱个体中有着不可忽视的HCV感染率,感染的危险因子似与性病及HBV感染有关。

Investigation of Hepatitis C Virus Infections among Heterosexuals with Multiple Partners and Patients with Sexually Transmitted Diseases

The seroprevalence of antibody against hepatitis C virus (HCV) was assesed by an enzyme-linked immunosorbent assay (ELISA) in 98 heterosexuals with multiple partners, 110 patients with sexually transmitted diseases (STDs), and 107 blood donors. The serum samples were also tested for hepatitis B surface antigen (HBsAg) and antibody for hepatitis B core antigen (anti-HBc). Of the patients with STDs 12.7% (14/110) were anti-HCV positive; of heterosexuals with multiple sexual partners, 4.1% (4/98) positive; of blood donors, 1.87% (2/107) positive. Among the 18 cases of HCV infection, 3 were positive for HBsAg and 10 were positive for anti-HBc. There was no relationship among HCV infection, sex and age in observed objects. From the present data, we can concluse that HCV infection can not be ignored in heterosexuals and patients with STDs and the risk factor for HCV infection appeared to be associated with a history of STDs and with HBV infection.