川芎嗪联合弥可保治疗糖尿病足的疗效观察

目的：观察川芎嗪联合弥可保治疗糖尿病足的疗效。方法：将60例糖尿病足患者随机分为治疗组与对照组各30例，两组均给予糖尿病的常规治疗。在此基础上，治疗组每日予川芎嗪联合弥可保治疗，对照组每日予复方丹参注射液联合维生素B12治疗。治疗6周后，比较两组治疗前后，陆床疗效和足背动脉血流动力学改变。结果：治疗组总有效率为90．0％，对照组为63．3％，两者有显著性差异（P〈0．05）。两组治疗前后彩色多普勒超声测定双侧足背动脉内径和血流速度，均有明显差异，但治疗组比对照组差异更显著（P〈0．05）。结论：川芎嗪联合弥可保治疗糖尿病足效果较好，不良反应少。

Effective observation on treating diabetic foot with TMP plus methylcobalamin

Objective： To observe the effect on treating diabetic foot with TMP plus methylcobalamin. Method： 60 patients were randomly divided into treatment group with 30 cases and control group with 30 cases, and both groups were given conventional treatment of diabetes. On this basis, treatment group was treated with TMP plus methylcobalamin and control group was treated in the compound Danshen injection plused treatment of vitamin B12 daily. Compare the clinical effect and the changes of dorsal artery blood flow velocity after the treatment for 6 weeks. Result： The total effective rate of the treatment was 90.0%, and the control group was 63.3%. There was a significant difference between the two groups （P〈0.05）. Two groups of color doppler ultrasound before and after treatment of bilateral dorsalis pedis artery diameter and blood flow velocity have significant differences, but the difference of treatment group was more significant than that of the control group. Conclusion： Treating diabetic foot with TMP plus methylcobalamin has better effect and less adverse reactions.