| 双波长分光光度法测定复方联苯苄唑霜剂中主药含量 |
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| 引用本文： | 王章阳,罗东,陈莉敏,金诚.双波长分光光度法测定复方联苯苄唑霜剂中主药含量[J].中国医院药学杂志,2001,21(1):17-18. |
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| 作者姓名： | 王章阳 罗东 陈莉敏 金诚 |
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| 作者单位： | 中国人民解放军第三军医大学附属西南医院, |
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| 摘 要： | 目的：建立复方联苯苄唑霜中氯霉素和联苯苄唑合含量测定方法。方法：采用双波长分光光度法消除组分间干扰进行含量测定。结果：氯霉素含量测定波长为276,237nm，对应平均回收率99.9%(RDS=0.8%,n=9)；联苯苄唑含量测定波长为256,295nm，对应平均回收率99.6%(RDS=1.3%,n=9)。结论：本方法简便、快速、准确。
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| 关 键 词： | 双波长分光光度法 氯霉素 联苯苄唑 复方联苯苄唑霜剂 抗真菌药 |
| 文章编号： | 1001-5213(2001)01-0017(02) |
| 修稿时间： | 2000年2月20日 |
Determination of main
ingredients in bifonazole cream compound by double wavelength spectrophotometric method |
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| WANG Zhang Yang,LOU Dong,CHENG Li Min,et al.Determination of main
ingredients in bifonazole cream compound by double wavelength spectrophotometric method[J].Chinese Journal of Hospital Pharmacy,2001,21(1):17-18. |
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| Authors: | WANG Zhang Yang LOU Dong CHENG Li Min |
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| Abstract: | OBJECTIVE:To develop a method for determining the contents of chloramphenicol and bifonazole in cream bifonazole compound.METHODS:The double wavelength spectrophotometric method was used for eliminating mutual interference.RESULTS:Measurement was carried out at 295,276,256,237 nm with a mean recovery of 99.9% ( RDS = 0.8% , n =9) for chloramphenicol and 99.6% ( RSD = 1.3% , n =9) for bifonazole.CONCLUSIONS:The method was simple and accurate. |
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| Keywords: | double wavelength spectrophotometric method chloramphenical bifonazole cream |
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