He-Ne激光照射对小鼠外周血IgG含量的影响

目的 :研究He-Ne激光照射对小鼠外周血IgG含量的影响 ,以便从外周血IgG含量的角度阐明其免疫调节效应。方法 :本试验以BALB/c小鼠为研究对象 ,应用 7.33,11.0 0 ,14 .6 7,2 2 .0 0和 36 .6 7J/cm2 五种剂量的氦氖激光作小鼠哈德尔氏腺照射 ,连续照射 8天 ,并于照射开始后第 3,6 ,9,13和第 17天动态监测实验鼠外周血IgG含量。结果 :以日剂量为 7.33,11.0 0 ,14 .6 7和 2 2 .0 0J/cm2 He -Ne激光照射小鼠后 ,外周血IgG含量均出现不同程度的升高 ,而 36 .6 7J/cm2 剂量组却呈现降低趋势。结论 :适当剂量的低能量激光照射可使小鼠外周血IgG含量增高 ,而过大剂量则对外周血IgG含量的产生起抑制效应

Study on the Effects of He-Ne Laser Irradiation on Peripheral Blood Serum IgG in Mice

Objective:The effects of He-Ne Laser Irradiation on peripheral blood serum IgG in Mice were studied,in order to illustrate mechanism of the immune modulation effect of He-Ne laser irradiation with the concentration changes of peripheral blood serum IgG in mice. Methods:By irradiating upon the inner corners of the mice eyes with He-Ne laser at five different dosages of 7.33, 11.00, 14.67,22.00 and 36.67J/cm 2 for eight days,the concentration of peripheral blood serum IgG were monitored kinetically at the 3rd, 6th, 9th, 13th and 17th day after laser irradiation. Results:The values of peripheral blood serum IgG increased in some degree at the 3rd,6th and 9th day in the groups of 7.33,11.00, 14.67 and 22.00J/cm 2, while the values decreased significantly in the group of 36.67J/cm 2. Conclusion:He-Ne laser with the proper dosages showed the up regulation effects on the concentration of peripheral blood serum IgG in mouse;while the large dose showed the down regulation effects.