藻蓝蛋白稳定性及稳态化的研究进展

藻蓝蛋白是一种存在于蓝藻、红藻和隐藻中的具有光捕获功能的天然水溶性色素蛋白，具有抗氧化、抗炎、抗癌、保肝和增强免疫力的特性。目前，藻蓝蛋白广泛用作食品着色剂、化妆品添加剂、临床诊断和免疫化学荧光试剂。然而，因藻蓝蛋白易受pH、光、温度、外源性物质等因素的影响而变性、沉淀和变色，使其在生产应用中受到限制，影响了其应用范围。因此，提高藻蓝蛋白的稳定性是扩大其工业生产应用的首要任务。本文对藻蓝蛋白的结构特性、稳定性影响因素及改善藻蓝蛋白稳定性的方法进行了综述，以期为提高藻蓝蛋白稳定性，拓展其应用范围提供理论参考。

Research progress on the stability and homeostasis of phycocyanin

Phycocyanin is a natural water-soluble pigment protein with light-harvesting function that exists in cyanobacteria, red algae and cryptophytes. It has the properties of anti-oxidation, anti-inflammatory, anti-cancer, liver protection and immunity enhancement. At present, phycocyanin is widely used as food coloring agent, cosmetic additive, clinical diagnosis and immunochemical fluorescence reagent. However, because phycocyanin is susceptible to denaturation, precipitation and discoloration due to factors such as pH, light, temperature, exogenous substances, etc., its production and application are restricted and its application range is affected. Therefore, improving the stability of phycocyanin is the primary task of expanding its industrial production and application. This article reviews the structural properties of phycocyanin, factors affecting stability, and methods to improve the stability of phycocyanin, in order to provide a theoretical reference for improving the stability of phycocyanin and expanding its scope of application.