心脏再同步治疗在心功能不良伴心房颤动患者中的临床疗效分析

目的 探讨心房颤动（房颤）患者经过房室结消融后心脏再同步治疗(CRT)的临床疗效。方法 将80例在本院接受CRT的心功能不良患者按术前心律分为两组：房颤组（15例）、窦性心律组(65例)，房颤组患者在CRT治疗同时行房室结消融。房室结消融和CRT术前收集患者基本信息如年龄、性别、心功能（NYHA分级）、病程、糖尿病和高...

The clinical response of cardiac resynchronization therapy in patients with heart failure and atrial fibrillation

Objective To investigate the clinical response of cardiac resynchronization therapy (CRT)and atrioventricular node (AVN) ablation in patients with heart failure and atrial fibrillation. Methods A total of 80 patients were included in the study,65 with sinus rhythm (SR) and 15 with atrial fibrillation(AF).Patients with atrial fibrillation were received CRT and AVN ablation. Clinical parameters (age,gender, NYHA functional class, course of disease, medical history, blood pressure, et al), NT-proBNP, QRS duration and echocardiographic parameters were collected at baseline,CRT-D ratio,drug, NYHA functional class,6-min walk test and echocardiographic parameters at 6-12 months after CRT were collected and compared. Stepwise multivaluables regression was performed to define whether the AF is independent determinants of them. Results Apart from left bundle branch block and left atrial diameter, baseline characteristics and clinical response after 6-12months between patients with SR or AF were comparable ( P＞0. 05 ). Stepwise multivaluables linear regression revealed that AF wasn' t independent determinant of the clinical response (P＞0. 05). Conclusion The present results demonstrate a similar benefit in heart function in both groups.