| 氮酮和二甲基亚砜促进常用抗生素皮肤吸收的比较研究 |
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| 引用本文： | 岳晓玉,李安生,李绍华,刘景忠.氮酮和二甲基亚砜促进常用抗生素皮肤吸收的比较研究[J].现代医学,1990(5). |
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| 作者姓名： | 岳晓玉 李安生 李绍华 刘景忠 |
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| 作者单位： | 中国医学科学院皮肤病研究所，中国医学科学院皮肤病研究所，中国医学科学院皮肤病研究所，中国医学科学院皮肤病研究所 南京 210042，南京 210042，南京 210042，南京 210042 |
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| 摘 要： | 用小鼠皮肤实验观察了氮酮(Azone)和二甲基亚砜(DMSO)对常用抗生素透皮吸收的影响,结果表明1—4％Azone可促进洁霉素、红霉素、新霉素和氯霉素的透皮吸收作用。40％DMSO可以促进氯霉素的透皮作用,而对其余三种抗生素无效。
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| 关 键 词： | 酮类 二甲亚砜 皮肤吸收 抗生素 |
The Comparative Study on Azone and Dimethyl Sulfoxide to Facilitate Percuta neous Absorption of Some Common Antibiotics |
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| Yue Xiaoyu.The Comparative Study on Azone and Dimethyl Sulfoxide to Facilitate Percuta neous Absorption of Some Common Antibiotics[J].Modern Medical JOurnal,1990(5). |
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| Authors: | Yue Xiaoyu |
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| Abstract: | The influence of Azone and Dimethyl sulfoxide(DMSO) on the percutaneous absorption of some common antibiotics was observed experimentally with the skin of mouses. The result showed that 1-4% Azone facilitated the percutaneous absorption of Lincomycin, Erythromycin, Neomycin and Chloromycin, and 40% DMSO only facilitated that of Chloromycin but didn' t influence upon the other three antibiotics. |
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| Keywords: | ketones dimethyl sulfoxide antibioties skin absorption |
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