功能性鼻内窥镜手术治疗上颌窦曲菌病

目的：探讨鼻内窥镜下非侵袭性上颌窦曲菌病的治疗及影响疗效的因素。方法：分析我院行功能性鼻内窥镜手术（Ｆｕｎｃｔｉｏｎａｌ ＥｎｄｏｓｃｏｐｉｃＳｉｎｕｓ Ｓｕｒ ｇｅｒｙ，ＦＥＳＳ）治疗的非侵袭性上颌窦曲菌病４１例的手术径路及抗真菌剂的使用对疗效及转归的影响。结果：双径路（经尖牙窝加下颌窦自然开口）术式的术后愈合期为４．７周，而单径路（经上颌窦自然开口）术式的术后愈合期为９．３周，两组差异有显著性意义（Ｐ〈０．０１），使用抗真菌剂冲洗术腔组的术后愈合期为６．４周，未使用抗真菌剂的术后愈合期为６．７周，但其差异无统计学意义（Ｐ〉０．０５），结论：ＦＥＳＳ是治疗非侵袭性上颌窦曲菌病的有效方法，双径路疗效优于单径路，是否用抗真菌剂冲术腔对疗效无明显影响。

Treatment of non-invasive aspergillosis of maxillary sinus by functional endoscopic sinus surgery

OBJECTIVE: To evaluate the treatment of non-invasive aspergillosis of the maxillary sinus by using functional endoscopic sinus surgery (FESS) and the correlated factors that affect the treatment. METHOD: 41 cases of local, non-invasive aspergillosis of the maxillary sinus undergone FESS were studied. RESULT: The period of convalescence of double pathway (via ostium of maxillary sinus and canine fossa) was 4.7 weeks while single pathway (via ostium of maxillary sinus only) was 9.3 weeks. There was significant difference (P < 0.01). The period of convalescence of group using anti-fungal drugs to wash the operative cavity was 6.4 weeks while the group without using drugs was 6.7 weeks. There was no statistic significance (P > 0.05). CONCLUSION: FESS is effective in treating of non-invasive aspergillosis of the maxillary sinus. The operation of double pathway is superior to that of single pathway. Whether to use antifungal drugs to wash the operative cavity has no obvious effect on the efficacy.