促红细胞生成素对慢性心力衰竭伴贫血患者脑钠肽和心功能的影响

【目的】探讨促红细胞生成素（EPO）对慢性心力衰竭（CHF）4#贫血患者脑钠肽（BNP）和心功能的影响。【方法】176例CHF伴贫血患者，随机分为治疗组和对照组，两组患者均给予常规抗心衰治疗，治疗组加用EPO注射及铁剂口服治疗，随访6个月，比较两组在BNP及心功能等指标上的差别。【结果】治疗组治疗前后BNP、运动耐力、贫血指标及心功能指标的改善均优于对照组（P〈0．05）。【结论】使用EPO治疗CHF伴贫血，可显著改善患者的临床症状及心功能。

Clinical Effects of Erythropoietin on Brain Natriuretic Peptide and Heart Function in Patients with Chronic Heart Failure Accompanied by Anemia

Objective] To explore the effects of erythropoietin （EPO） on brain natriuretic peptide （BNP） and heart function in patients with chronic heart failure（CHF） accompanied by anemia. Methods] Seventy six patients with CHF accompanied by anemia were divided at random into treatment group and control group. Both groups received regular anti-heart failure treatment and treatment group received additional injection of EPO and oral ehalybeate. After six-month follow-up, the difference in objective indices was compared. Results] There was significant improvement in BNP, exercise capacity, Hb levels and heart function in EPO group （P 〈0.05）, but there were no significant changes in control group（ P 〉0.05）. Conclusion] EPO treatment can significantly improve the clinical symptoms and heart function of patients with CHF accompanied by anemia.