不同干燥方式对桑枝提取物物理指纹图谱及其总黄酮含量的影响

目的:考察不同干燥方式对桑枝提取物物理指纹图谱及其总黄酮含量的影响。方法:分别采用常压干燥、减压干燥及冷冻干燥对桑枝浸膏进行干燥,并测定其总黄酮含量,构建以雷达图直观展现的桑枝提取物物理指纹图谱,对3种不同干燥方式所得桑枝提取物物理指纹图谱进行比较,通过可压参数比较不同干燥方式所得桑枝提取物的压缩特性。结果:不同干燥方式所得桑枝提取物对照物理指纹谱相似度77. 8%~87. 3%,一级指标平均值及可压参数的RSD处于0~16. 6%,除均一性及稳定性外,其余RSD均10%。不同干燥方式对桑枝提取物稳定性及均一性影响较大,对其他因素影响较小。结论:不同干燥方式对桑枝提取物物理指纹图谱有一定的影响,而对桑枝总黄酮含量影响较小。

Effect of Different Drying Methods on Physical Fingerprint and Total Flavonoids Content of Mori Ramulus Extract

Objective: To investigate the influence of different drying methods on physical fingerprint and total flavonoids content of Mori Ramulus extract.Method: The Mori Ramulus extract was dried by freeze drying,vacuum drying,ambient pressure drying,respectively.The content of total flavonoids in samples with different drying methods were determined and compared with each other.Physical fingerprint of Mori Ramulus extract was established by radar map and the physical fingerprint of samples with different drying methods were compared with each other.In the meantime,compressible parameters were employed to analyze the compressibility characteristics of Mori Ramulus extract treated by different drying methods.Result: Similarity of control physical fingerprint of Mori Ramulus extract treated by different drying methods was 77.8%-87.3%,relative standard deviation(RSD) of average value of the first level indexes and the compressible parameters was 0-16.6%.Except for homogeneity and stability,the remaining RSDs were less than 10%.Effects of different drying methods on homogeneity and stability of Mori Ramulus extract were greater than that of other factors.Conclusion: Different drying methods have certain effects on physical fingerprint of Mori Ramulus extract,but they have little influence on total flavonoids content in Mori Ramulus extract.