1994-2013年黔南州6县（市）农村布依族居民 血清总胆固醇水平的变化特点分析

摘要:目的　分析黔南州6县（市）农村布依族居民1994-2013年间血清总胆固醇（TC）水平及高胆固醇血症患病率的变化特点。方法　1994年，在黔南州北部长顺县、惠水县、都匀市，南部的平塘县、独山县、罗甸县6县（市）25～64岁农村布依族居民进行了心血管病危险因素调查，建立心血管病研究队列。2013年，在该队列人群中再次进行心血管病危险因素的调查，对2次调查资料完整的2833名研究对象的血清TC进行分析。结果　2013年复查时布依族女性居民TC平均为（5.49±0.92）mmol/L，男性为（4.96±0.76）mmol/L，女性TC水平平均值与男性比较，差异有统计学意义（t＝16.56，P＝0.000）；20年来黔南州6县（市）农村布依族男性居民TC水平增加0.51 mmol/L，上升11.46%。女性TC水平增加0.81 mmol/L，上升17.31%，女性上升幅度高于男性；不同年龄段比较，25～34岁年龄段TC水平增加的幅度最大。不同地点比较，黔南北部惠水县和黔南南部罗甸县人群TC水平增加值最大，分别为0.96 mmol/L和1.01 mmol/L。黔南州6县（市）农村布依族居民高胆固醇血症患病率从5.11%增加到10.80%，增加了1.12倍。结论　20年来黔南州6县（市）农村布依族居民TC平均水平呈持续增高趋势，25～34岁年龄段增加的幅度最大，女性上升幅度高于男性。黔南南部和北部TC水平平均值比较无差异性。

Analysis of serum total cholesterol level of rural Buyi residents in 6 counties (cities) of Qiannan from 1991 to 2013

Abstract: Objective This study was to analyze the change characteristics of serum total cholesterol (TC) level and the prevalence of hypercholesterolemia among rural Buyi residents in six counties (cities) of Qiannan from 1994-2013. Methods In 1994, cardiovascular disease risk factor investigation was carried out to rural Buyi residents of 25-64 years old in six counties (cities) of Changshun County, Huishui County, Duyun City in north of Qiannan, and Pingtang County, Dushan County and Luodian County in south of Qiannan, to establish cardiovascular disease research queue. In 2013, cardiovascular disease risk factor investigation was conducted again to the people in the queue, and analyzed the serum TC of 2833 objects received both investigations. Results In 2013, average TC of female Buyi residents was 5.49±0.92 mmol/L, and that of male Buyi residents was 4.96±0.76 mmol/L. From 1994 to 2013, TC level of these rural male Buyi residents increased 0.51mmol/L, which went up 11.46%. The level of female residents increased 17.31%, with a higher increment in comparison to that of male residents. No matter which gender, the increase was the highest in the age group of 25-34 years old. In terms of location, the increase in TC level was 0.96 mmol/L in Huishui County of north Qiannan and 1.01 mmol/L in Luodian County of south Qiannan, which was the highest increase. From 1994 to 2013, the prevalence of hypercholesterolemia among rural Buyi residents in six counties (cities) of Qiannan increased from 5.11% to 10.80%. Conclusion The mean TC level of residents in six counties (cities) of Qiannan kept increasing during1994-2013, especially in the age group of 25-34 years old and the female. No significant difference in TC level was observed between the south and north of Qiannan.