脾部分栓塞术治疗脾功能亢进

目的 通过部分脾栓塞术治疗各种原因引起的继发性脾亢和原发性脾亢。方法 28例肝硬化脾功能亢进、肝癌合并脾功能亢进及其它原因引起的巨脾患者，分别经股动脉穿刺引入COBRA导管或肝导管超选择至脾脏中、下部分进行动脉造影，采用1mm左右的明胶海绵碎块＋庆大霉素＋造影荆进行栓塞。结果 最先发生反应的是白细胞升高，其次是血小板升高，脾脏体积逐渐缩小及肝功能改善。结论 PSE既能抑制亢进的脾功能，又能保留脾脏的正常免疫功能和预防感染的能力，具有适应证广、简便、安全、效果显著、创伤小、并发症少、费用低廉等优点，是替代外科脾切除的首选治疗方法。

Application of Partial Spleen Embolization in Treating Hypersplenism

Objective To investigate the application of partial spleen embolization (PSE) in treating idiopathic and insecondary hypersplenism caused by diversified reason. (Methods) 28 patients with hypersplenism caused by hepatic cirrhosis or hepatoma or other reason were embolismed by using gelatin sponge (diameter 1mm or so) and cidomycin and constrast medium. Results Firstly,the white blood cell began to increase, secondly,the platelet began to increase and the cubic capacity of spleen deflated little by little and liver function was improved. Conclusion PSE can repress hypersplenism,while can retain normal immune function and prevent infection. PSE have some forte : extensive indication,little complication,small trauma and visible effect; it is a safe and simple method. It is a preferred therapy method to take the place of splenectomy.