| 大鼠中缝背核内一氧化氮合酶阳性神经元向伏隔核的投射 |
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| 引用本文： | 龚鑫,熊克仁,赵健.大鼠中缝背核内一氧化氮合酶阳性神经元向伏隔核的投射[J].皖南医学院学报,2006,25(2):87-88. |
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| 作者姓名： | 龚鑫 熊克仁 赵健 |
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| 作者单位： | 皖南医学院,解剖学教研室,安徽,芜湖,241001 |
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| 基金项目： | 皖南医学院校科研和教改项目 |
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| 摘 要： | 目的:观察大鼠中缝背核内一氧化氮合酶(NOS)阳性神经元向伏隔核的投射,为阐明一氧化氮(NO)在中缝背核与伏隔核的纤维联系中的作用提供有价值的形态学依据。方法:用还原型尼克酰胺腺嘌呤二核苷酸脱氢酶(NADPH d)法结合辣根过氧化物酶(HRP)逆行追踪法,观察大鼠中缝背核内NOS阳性神经元向伏隔核的投射。结果:在中缝背核内观察到HRP/NOS双标记神经元,所占比例为5%。结论:中缝背核内有NOS阳性神经元向伏隔核投射。
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| 关 键 词： | 中缝背核 伏隔核 一氧化氮合酶 辣根过氧化物酶 大鼠 |
| 文章编号： | 1002-0217(2006)02-0087-02 |
| 收稿时间： | 2005-09-26 |
| 修稿时间： | 2005年9月26日 |
The projection of nitric oxide synthase (NOS) positive neurons in dorsal raphe nucleus to the nucleus accumbens in rats |
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| GONG Xin,XIONG Ke-ren,ZHAO Jian.The projection of nitric oxide synthase (NOS) positive neurons in dorsal raphe nucleus to the nucleus accumbens in rats[J].Acta Academiae Medicinae Wannan,2006,25(2):87-88. |
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| Authors: | GONG Xin XIONG Ke-ren ZHAO Jian |
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| Affiliation: | Department of Anatomy, Wannan Medical College, Wuhu 241001, China |
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| Abstract: | Objective:To observe the projection of nitric oxide synthase(NOS) positive neurons in dorsal raphe nucleus to the nucleus accumbens in rats, and to provide valuable morphological bases for clarifying the role of nitric oxide(NO) in the fibres between dorsal raphe nucleus and nucleus accumbens. Methods: The way of nicotinamide adenosine dinucleotide phosphate diaphorase(NADPH-d) associated with horseradish peroxide enzyme(HRP) retrograde tracing was used to study the projection of NOS positive neurons in dorsal raphe nucleus projecting to the nucleus accumbens in rats. Results: HRP/NOS double labeling neurons were found in dorsal raphe nucleus and the percentage was 5%. Conclusion: The projection of NOS positive neurons to nucleus accumbens can be found in dorsal raphe nucleus. |
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| Keywords: | dorsal raphe nucleus nucleus accumbens nitric oxide synthase horseradish peroxide enzyme rats |
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