| 门脉高压患者降钙素基因相关肽、神经肽y与醛固酮检测及意义 |
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| 引用本文： | 张莉娟,王小众,李斌,黄月红,陈治新.门脉高压患者降钙素基因相关肽、神经肽y与醛固酮检测及意义[J].中西医结合肝病杂志,2000,10(6):7-11. |
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| 作者姓名： | 张莉娟 王小众 李斌 黄月红 陈治新 |
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| 作者单位： | 福建医科大学附属协和医院,福州,350001 |
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| 基金项目： | 福建省自然科学基金项目(No:C96042) |
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| 摘 要： | 目的研究降钙素基因相关肽(CGRP)、神经肽y(NPY)与醛固酮(ALD)在门脉高压症发病中的作用.方法应用放射免疫学方法对30例门脉高压症患者、30名正常对照者的血浆以及20例门脉高压症患者的腹水进行CGRP、NPY与ALD的检测.结果门脉高压症组患者血浆CGRP、NPY与ALD水平分别为125.95±35.43pg/ml、88.49±52.51pg/ml及868.5±459.6pg/ml,正常对照组分别为69.14±23.29pg/ml、151.54±38.51pg/ml及306.4±124.3pg/ml,两组差别有显著意义(P＜0.05),腹水组分别为81.83±38.55pg/ml、61.47±28.35pg/ml及216.7±186.1pg/ml.腹水CGRP与正常对照组相比差异无显著意义,腹水NPY与ALD含量低于正常对照组(P＜0.05).其中有腹水者NPY低于无腹水者,而CGRP与ALD水平高于无腹水者(P＜0.05).结论血浆CGRP、NPY与ALD均在肝硬变门脉高压发病的病理生理机制中起作用.
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| 关 键 词： | 门脉静永压 肝硬变 降钙素基因相关肽 神经肽y |
Measurement and Significance of Calcitonin Gene-related Peptide、 Neuropeptide Y and Aldosterone in Portal Hypertension |
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| Zhang Lijuan,Wang Xiaozhong,Li Bin,et al..Measurement and Significance of Calcitonin Gene-related Peptide、 Neuropeptide Y and Aldosterone in Portal Hypertension[J].Chinese Journal of Integrated Traditonal and Western Medicine on Liver Diseases,2000,10(6):7-11. |
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| Authors: | Zhang Lijuan Wang Xiaozhong Li Bin |
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| Affiliation: | Zhang Lijuan,Wang Xiaozhong,Li Bin,et al. The Affiliated Union Hospital,Fujian Medical University |
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| Abstract: | |
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| Keywords: | Portal Hypertension Liver Cirrhosis Calcitonin Gene-Related Peptide (CGRP) Neuropeptide Y (NPY) Aldosterone (ALD) |
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