| THE MEASUREMENT AND APPLICATION OF TSH-IRMA LEVELS AMONG DIFFERENT AGE GROUPS IN AREAS WITH IODINE DEFICIENCY DISORDERS |
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| 作者姓名： | 时立新 时钟孚 张家秀 马启铃 孔德明 杨礼福 谭英 |
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| 作者单位： | Endocrine Unit，Affiliated Hospital of Guiyang Medieal College，Guiyang 550004 |
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| 摘 要： | ＴＨＥＭＥＡＳＵＲＥＭＥＮＴＡＮＤＡＰＰＬＩＣＡＴＩＯＮＯＦＴＳＨ－ＩＲＭＡＬＥＶＥＬＳＡＭＯＮＧＤＩＦＦＥＲＥＮＴＡＧＥＧＲＯＵＰＳＩＮＡＲＥＡＳＷＩＴＨＩＯＤＩＮＥ ＤＥＦＩＣＩＥＮＣＹ ＤＩＳＯＲＤＥＲＳＳｈｉＬｉｘｉｎ（时立新）；ＳｈｉＺｈｏ...
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| 关 键 词： | 碘缺乏病 放射免疫法 TSH 血清学检查 碘盐 疾病监测 |
THE MEASUREMENT AND APPLICATION OF TSH-IRMA LEVELS AMONG DIFFERENT AGE GROUPS IN AREAS WITH IODINE DEFICIENCY DISORDERS |
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| Shi Lixin, Shi Zhongfu, Zhang Jiaxiu,Ma Qilin ,Kong Deming,Yang Lifu and Tan Ying.THE MEASUREMENT AND APPLICATION OF TSH-IRMA LEVELS AMONG DIFFERENT AGE GROUPS IN AREAS WITH IODINE DEFICIENCY DISORDERS[J].Chinese Medical Sciences Journal,1995,10(1):30-33. |
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| Authors: | Shi Lixin Shi Zhongfu Zhang Jiaxiu Ma Qilin Kong Deming Yang Lifu and Tan Ying |
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| Abstract: | Using immunoradiornetric TSH assay (TSH-IRMA) to measure whole blood TSH levels spotted onto filter paper, we compared TSH levels among different age groups (neonates, <1 yr infants, schoolchildren aged 7 to 14 yrs, adults,pregnant women and reproductive-age women) in Guiyang, where iodine deficiency has long been a problem. The results showed: 1) The percentage of subjects with TSH levels equal to or greater than 5 mIU/L in the neonate group was 38.9% while the percentages in the other groups were 0-3.3% (P<0.01); 2)The TSH levels of the neonates were inversely related to the urinary iodine values of their mothers (pregnant women). (r=-0. 5, P<0. 01);3)97.6% of the inhabitants in Guiyang ingested salt with less than 20mg/kg iodine. The results indicate that iodine deficiency remains a problem in Guiyang. Neonates are the only ideal population for monitoring iodine deficiency. |
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| Keywords: | TSH iodine deficiency |
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