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100例“抑郁发作“首次住院药物治疗分析
引用本文:程烈,任婉文,韩耀静.100例“抑郁发作“首次住院药物治疗分析[J].上海精神医学,2003,15(2):90-92.
作者姓名:程烈  任婉文  韩耀静
作者单位:310013,杭州市第七人民医院
摘    要:目的了解"抑郁发作"患者首次住院应用抗抑郁药及合并用药情况,以便对临床合理用药提供参考.方法采用CCMD-3,对1997年1月~2002年6月份,在我院首次住院,诊断为"抑郁发作"的患者,男女各50例,对患者临床应用的抗抑郁药和合并用药的分布、频度及副反应进行分析.结果首次住院的"抑郁发作"患者在使用抗抑郁药物治疗中,其药物的品种、使用频度均在逐年变化,第一代抗抑郁药物使用频度逐年下降,而第二代抗抑郁药物则逐年上升;第一代抗抑郁药副反应大于第二代抗抑郁药,两代抗抑郁药联合应用,疗效并不增加,而副反应明显大于单一用药;苯二氮(艹卓)类药物较普遍,占88.00%以上.结论"抑郁发作"首次住院患者的抗抑郁药临床应用基本合理,疗效确切.第二代抗郁药越来越多的被临床医生和患者接受,其用药比例逐年增加.苯二氮(艹卓)类药物在抗抑郁治疗中有滥用之势,其副反应应引起临床医生的高度重视.

关 键 词:抑郁发作  药物治疗

Analysis of drug therapy of first hospitalization of 100 patients with depressive episode
CHEN Lie,Ren Wanwen,Han Yaojing.Analysis of drug therapy of first hospitalization of 100 patients with depressive episode[J].Shanghai Archives of Psychiatry,2003,15(2):90-92.
Authors:CHEN Lie  Ren Wanwen  Han Yaojing
Abstract:Objectives: To analyse the antidepressants and combined drug therapy for the first hospitalization of patients with depressive episode. Method: The drug therapy of 50 male patients and female patients from 1997.1 to 2002.6 who met the criteria of CCMD 3 for depressive seisode were analysed. Results: The second generation of antidepressants were used more common compared to the first one. Benzodiazepine was widely used. Conclusion: The clinical use of antidepressants was rational and that of the second generation of antidepressant increased yearly.
Keywords:Depressive episode  Drug therapy
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