消胃炎散治疗胃粘膜腺体肠土皮化生和不典型增生的临床研究

本文报告应用消胃炎散治疗胃粘膜肠化和不典型增生的临床研究结果。随机分为治疗组和对照组。结果:治疗组对肠化的总有效率为91.30%,对不典型增生的总有效率为92.16%;而对照组对肠化和不典型增生的有效率分别为21.23%和14.46%。治疗组疗效显著优于对照组(P<0.01)。

Clinical Study on Treatment of Intestinal Metaplasia and Atypical Hyperplasia of Gastric Mucosa with Xiao Wei Yan Powder

138 cases of intestinal metaplasia (IM) and 104 cases of atypical hyperplasia (AH) of the gastricmucosa of chronic gastritis treated with Xiao Wei Yan Powder (XWYP) were reported. Thediagnoses were based on the pathological examination of gastric antrum biopsy specimens. Thecases were randomly divided into treated group and control group. The XWYP contained Smilaxglabrae, Hedyotis diffusae, Taraxacum mongolicum, Caesalpinia sappan, Paeonia alba, Cyperus rotun-dus, Bletilla striata, Glycyrrhiza uralensis etc., and was prepared in powder form, taken orally 5-7g tid.After 2-4 month of administration, gastroscopic and pathological examinations were repeated.Results: In treated group, the total effective rate of IM was 91.3% and that of the AH was 92.16%,while in coatrol group, they were 21.3% and 14.46% respectively (P<0.01). It denoted that XWYPhad marked therapeutic effects for IM and AH. The animal experiments revealed no toxic effect, sosafety guarantee was provided for its clinical application.