2011年西宁地区儿童腹泻病毒流行病学调查

目的:对2011年西宁市腹泻病毒进行流行病学调查,对青海省腹泻病毒流行株和流行趋势进行统计分析,为腹泻病毒引起的腹泻提供实验室资料,更好地控制病毒性腹泻的流行。方法:用巢式PCR和多重PCR方法对西宁地区488例婴幼儿腹泻标本进行腹泻病毒检测。结果:西宁地区腹泻儿童中腹泻病毒的检出率分别为:轮状病毒A组阳性33例(6.76%),其中G9型15例、G3型13例、P6型1例、P8型2例、P9型2例;轮状病毒B/C组阳性3例(0.61%);杯状病毒阳性23例(4.71%),其中扎如病毒17例、诺如病毒GⅡ型6例;星状病毒阳性7例(1.43%)。结论:轮状病毒A组和杯状病毒是西宁地区婴幼儿腹泻的主要病原体之一。

Epidemiological investigation on diarrhea virus among children in Xining area in 2011

Objective:To conduct an epidemiological investigation on diarrhea virus in Xining city in 2011,analyze epidemic strains and trend of diarrhea virus in Qinghai province,and provide experimental data for diarrhea induced by diarrhea virus to control prevalence of diarrhea virus.Methods:Nest-PCR and multiplex PCR were used to detect diarrhea virus among 488 infants in Xining area.Results:The detection rates of diarrhea virus in children with diarrhea in Xining area: group A rotavirus(6.76%,33 children,including 15 children of G9 type,13 children of G3 type,1 child of P6 type,2 children of P8 type,and 2 children of P9 type),group B/C rotavirus(0.61%,3 children),calicivirus(4.71%,23 children,including 17 children with sapovirus and 6 children with norovirus of GⅡ type),astrovirus(1.43%,7 children).Conclusion:Group A rotavirus and calicivirus are main pathogens of infantile diarrhea in Xining area.