Neuroform自膨式支架联合弹簧圈栓塞治疗颅内宽颈动脉瘤的疗效分析

目的:探究Neuroform自膨式支架联合弹簧圈栓塞治疗颅内宽颈动脉瘤的临床疗效。方法:接受介入治疗的颅内宽颈动脉瘤患者152例纳入研究,根据治疗方法不同分为非支架辅助弹簧圈栓塞组(单纯弹簧圈组)56例和支架辅助弹簧圈栓塞组(支架辅助组)96例。回顾性分析患者的临床资料,比较2组治疗一般情况、并发症发生率、术前及出院时美国国立卫生院脑卒中量表(NIHSS)评分及格拉斯哥昏迷量表(GCS)评分、复发率及预后。结果:2组手术时间、术后住院时间及随访时间差异无统计学意义(P>0.05)。出院时支架辅助组NIHSS评分低于单纯弹簧圈组,GCS分数高于单纯弹簧圈组(P<0.05)。2组并发症发生率差异无统计学意义(P>0.05)。随访期间,支架辅助组复发率及mRS评分低于单纯弹簧圈组(P<0.05)。结论:对于蛛网膜下腔出血颅内宽颈动脉瘤患者,在弹簧圈栓塞的基础上联合Neuroform自膨式支架可明显提高疗效,同时降低动脉瘤的复发率,安全性高。

Therapeutic Effect of Neuroform Self-Expanding Stent Combined with Spring Coils in Treatment of Intracranial Wide-Necked Aneurysms

To explore the therapeutic effect of the Neuroform self-expanding stent combined with spring coils in the treatment of intracranial wide-necked aneurysm. Methods: A total of 152 patients who accepted intervention for intracranial wide necked aneurysms were recruited to the study and divided according to treatment method into the non-stent-assisted coil embolization group (coil only group, 56 cases) and the stent-assisted coil embolization group (stent-assisted group, 96 cases). Clinical data of all the patients were retrospectively analyzed. General treatment circumstances, incidence of complications, National Institute of Health Stroke Scale (NIHSS) scores and Glasgow Coma Scale (GCS) scores before operation and at time of patient release, recurrence rate, and prognosis were compared between the two groups. Results: There were no significant differences between the two groups with regards to operation time and postoperative hospitalization time (P>0.05). At the time of patient release, the NIHSS score of the stent-assisted group was lower than that of the coil only group, and the GCS score of the stent-assisted group was higher than that of the coil only group (P< 0.05). There was no significant difference between the incidence of complications in the two groups. During the follow-up period, the recurrence rate and mRS score in the stent-assisted group were lower than those in the coil only group (P<0.05). Conclusion: For patients with intracranial wide-necked aneurysms with subarachnoid hemorrhage, the combination treatment of neuroform self-expanding stent with coil embolization can safely and significantly improve the curative effect and decrease the recurrence rate.