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锌对新生大鼠海马培养神经元生长发育的作用
引用本文:王福庄,丁爱石.锌对新生大鼠海马培养神经元生长发育的作用[J].营养学报,1995,17(4):357-362.
作者姓名:王福庄  丁爱石
作者单位:北京军事医学科学院基础医学研究所
摘    要:采用无血清培养的新生大鼠海马神经细胞,观察锌对脑细胞生长发育的作用。结果表明,锌能促进体外培养海马神经元的神经突起生长,突起数增多;神经元的活存数和神经元胞体的直径和面积增加。用流式细胞术分析证明,神经元总蛋白含量增高。本结果提示,锌对海马神经元的生长发育具有促进作用

关 键 词:锌,海马,神经元,细胞培养

THE EFFECT OF ZINC ON GROWTH AND DEVELOPMENT OF NEW BORN RAT HIPPOCAMPAL NEURONS
Wang Fuzhuang,Ding Aishi,Wei Wen,Zhang Shuangxi,Hiang Yanhua.THE EFFECT OF ZINC ON GROWTH AND DEVELOPMENT OF NEW BORN RAT HIPPOCAMPAL NEURONS[J].Acta Nutrimenta Sinica,1995,17(4):357-362.
Authors:Wang Fuzhuang  Ding Aishi  Wei Wen  Zhang Shuangxi  Hiang Yanhua
Abstract:he effect of zinc on the growth and development of hippocampal neu-rons was observed in the cell culture of serum free medium.The results sh-owed that both the number of stirvival cells and the outgrowth of neurites were increased by zinc in cultured hippocampal neurons.In the presence of zinc,the diameter and volume of neurons as well as the content of pro-tein in the cells were markedly increased in image analysis and FACS.It suggested that zinc might play a promotive role in the growth and deve-lopment of hippocampal neuron.
Keywords:zinc    hippocampal neuron  cell culture  
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