| 三河牛DGAT1基因K232A位点与产奶性状的关联分析 |
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| 引用本文： | 卢振峰,刘莉莉,赵国丽,秦春华,杨艳,俞英,吴宏军,刘爱荣,史远刚,王雅春.三河牛DGAT1基因K232A位点与产奶性状的关联分析[J].中国奶牛,2014(3):13-16. |
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| 作者姓名： | 卢振峰 刘莉莉 赵国丽 秦春华 杨艳 俞英 吴宏军 刘爱荣 史远刚 王雅春 |
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| 作者单位： | [1]中国农业大学动物科技学院,北京100193 [2]宁夏大学动物科技学院,银川750021 [3]宁夏正鑫牧业科技发展有限公司,银川750020 [4]北京市园林学校动物系,北京102488 [5]内蒙古谢尔塔拉种牛场,海拉尔021008 [6]内蒙古自治区海拉尔农垦集团有限公司,海拉尔021008 |
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| 基金项目： | 国家科技攻关计划项目（编号：2011BAD28802）.现代农业产业技术体系专项资金项目（编号：CARS-37）.长江学者与创新团队发展计划项目（编号：IRTll91）和国家自然科学基金项目（编号：31172191）资助. |
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| 摘 要： | 二酰甘油酰基转移酶（DGATI）基因K232A位点是一个与奶牛产奶性能有关的重要位点。、本研究通过对三河牛K232A位点检测发现，该位点在三河牛中处于Hardy—Weinberg平衡状态，说明没有经过选择。KK基因型个体具有最低的体细胞评分和最高的乳脂率；KA基因型个体具有最高的产奶量和乳脂量；AA基因型个体具有最高的乳蛋白量。K等位基因有利于提高乳脂率和乳脂量，同时降低体细胞评分。在三河牛群体中，K等位基因的基因频率为0．23，利用K4k点来提高乳脂率和乳脂量以及降低体细胞评分，存在很大的选择空间。
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| 关 键 词： | 三河牛 二酰甘油酰基转移酶基因（DGATl） K232A 产奶性状 |
Association of K232A in DGAT1 Gene with Milk Production Traits in Sanhe Cattle |
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| LU Zhen-feng,LIU Li-li,ZHAO Guo-li,QIN Chun-hua,YANG Yan,YU Ying,WU Hong-jun,LIU Ai-rong,SHI Yuan-gang,WANG Ya-chun.Association of K232A in DGAT1 Gene with Milk Production Traits in Sanhe Cattle[J].China Dairy Cattle,2014(3):13-16. |
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| Authors: | LU Zhen-feng LIU Li-li ZHAO Guo-li QIN Chun-hua YANG Yan YU Ying WU Hong-jun LIU Ai-rong SHI Yuan-gang WANG Ya-chun |
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| Affiliation: | 1. College of Animal Science ＆ Technology, China Agricultural University, Beijing 100193; 2. College of Animal Science ＆ Technology, Ningxia University, Yinchuan 750021; 3. Ningxia Sinogen Farming Sic-Tec Development Co., Ltd., Yinchuan 750020; 4. Department of Animal Science, Beijing Landscape Architecture School, Beijing 102488; 5. Inner Mongolia Xieertala Bull Station, Hailar 021008; 6.Inner Mongolia Hailar Agricultural Reclamation Group co., LTD, Hailar 021008) |
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| Abstract: | The K232A mutation in the diacylglycerol acyl transferase I（DGAT1） gene was reported to have significant effects on milk production traits in cattle. The polymorphisms of K232A were detected in this study. The result showed that it was in Hardy-Weinberg equilibrium, which mean that this mutation was not uder selection in the Sanhe population. Cows with KK genotype had the lowest somatic cell score and the highest fat percentage. Cows with KA genotype had the highest milk yield and fat yield. Cows with AA genotype had the highest protein yield. Allele K could reduce somatic cell score （SCS） and improve fat percentage and fat yield. In the Sanhe cattle population, the allelic frequency of K at K232A site was 0.23. In theory, it is feasible to use K allele to improve the fat yield and fat percentage and reduce the SCS in the Sanhe population. |
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| Keywords: | Sanhe cattle Diacylglycerol acyl transferase 1 （DGAT1） K232A Milk production traits |
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