| 啶虫脒/羧甲基壳聚糖缓释微球性能研究 |
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| 引用本文： | 李芝,李卫宁,王志.啶虫脒/羧甲基壳聚糖缓释微球性能研究[J].安徽农业科学,2011,39(15):9022-9023. |
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| 作者姓名： | 李芝 李卫宁 王志 |
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| 作者单位： | 河北农业大学理学院; |
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| 基金项目： | 河北省科学技术研究与发展计划结转项目(07220701D-5); 保定市科学技术研究与发展指导计划(10ZN006); 河北农业大学非生命学科与新兴学科科研发展基金 |
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| 摘 要： | 目的]探索啶虫脒/羧甲基壳聚糖缓释微球的最佳制备条件。方法]以啶虫脒为囊心药物,以羧甲基壳聚糖-阿拉伯胶-明胶作为载体材料,采用锐孔法制备啶虫脒缓释凝胶微球,以包封率为参考指标,通过正交试验探究啶虫脒缓释微球的最佳制备条件,并探讨壳聚糖缓释微球对啶虫脒的缓释性能。结果]啶虫脒缓释微球的最佳制备条件为：25 g/L羧甲基壳聚糖、羧甲基壳聚糖-啶虫脒的浓度比为2∶1、1.5%氯化钙、戊二醛浓度为5%。所制备的啶虫脒/羧甲基壳聚糖-阿拉伯胶-明胶缓释凝胶微球的包封率达48.56%,并具有很好的缓释性能,缓释时间达60 h以上。结论]制得的羧甲基壳聚糖-阿拉伯胶-明胶微球对啶虫脒有控制释放的作用。
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| 关 键 词： | 啶虫脒 羧甲基壳聚糖 缓释/控释 |
Study on the Preparation and Properties of Carboxymethyl Chitosan-gelatin Slow-releasing Gel Beads for Acetamiprid |
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| LI Zhi et al.Study on the Preparation and Properties of Carboxymethyl Chitosan-gelatin Slow-releasing Gel Beads for Acetamiprid[J].Journal of Anhui Agricultural Sciences,2011,39(15):9022-9023. |
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| Authors: | LI Zhi |
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| Affiliation: | LI Zhi et al(College of Sciences,Agricultural University of Hebei,Baoding,Hebei 071001) |
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| Abstract: | Objective]The research aimed to discuss the optimum preparation conditions of carboxymethyl chitosan-gelatin slow-releasing gel beads for acetamiprid.Method] With acetamiprid as base materials,with carboxymethyl chitosan-acacia and gelatin as the carrier material,the slow-releasing microspheres containing acetamiprid was prepared by using microsphere method.With the encapsulation rate as reference index,the optimum preparation conditions of slow-releasing microspheres containing acetamiprid were discussed... |
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| Keywords: | Acetamiprid Carboxymethyl chitosan Delayed release/controlled release |
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