心肺在动脉粥样硬化形成中病机学意义简

动脉粥样硬化（atherosclerosis，AS）是本虚标实之病，心肺在AS的形成中有着至关重要的意义。肝、脾、肾虚是“痰浊积聚”的内在原因，肺失治节与心火不炎、心火炎化不正，是痰浊入血的关键因素。痰浊积郁化毒损伤脉道及火热灼伤脉道，是痰浊能着于脉道之外因；心不主脉，及肺不辅心主脉，脉不能固摄，是痰浊瘀血能着于脉道之内因。心火之炎化、肺金之革伐亦能复血之精清，复脉之疏通条达。因此心、肺在AS的形成中有着至关重要的意义。

Significance of Heart and Lung for Pathogenesis of Atherosclerosis in Traditional Chinese Medicine

Atherosclerosis is a kind of root deficiency and branch excess disease according to the traditional Chinese medicine （ TCM ） theory, and the cardiopuhnonary functions were of vital significance in the AS formation. Liver, spleen and kidney deficiencies were the pathological bases of the TCM syndrome of turbid phlegm accumulation, the lung maladjustment, heart-fire non-flaming up and heart-fire flaming- up but disharmony were the critical factors for the turbid phlegm accumulation in blood. The stasis of turbid- phlegm and transforming to toxicity resulted in the injury of pulse-vessel and pulse-vessel injured by fire and heats were the exogenous pathological mechanism of turbid-phlegm gathering the pulse-vesseL And the immanent causes were the non-administrating and unregulating pulse functions of the heats, unassisted regulatory function of the lungs for heats and incontinence functions of the pulse-vessel. The heart-fire flaming-up and regulatory functions of the lungs could regain the purifying and essence of the blood and the patency of the blood vessels as well. Therefore, the heart and lung were the key to the pathogenesis and development of atherosclerosis disease.