藏药旺拉毒理学安全性实验研究

目的评价藏药旺拉作为药品和食品二用功效的食用安全性。方法采用大、小鼠急性经口毒性试验、小鼠骨髓微核试验、小鼠精子畸形试验3、0 d喂养试验进行检测。结果雌雄大、小鼠经口LD50大于10.00 g/kg体重,属实际无毒级;骨髓微核试验、精子畸形试验、遗传毒性试验均为阴性;30 d喂养试验未显示明显毒性。结论藏药旺拉食用安全。

Toxicological Evaluation of the Safty of Tibetan Drug Wangla

Objective To evaluate the benefits and safety of Tibetan drug Wangla as a food and as a drug.Methods Rats and mice were used in this experiment.Tests of acute oral toxicity,micronucleus assay of mouse bone marrow,sperm abnormality test and 30 days-feeding test were performed.Results All oral LD50 of the drug Wangla in male and female rats and mice were >10.00 g/kg body weight.It is actually non-toxic.All results of micronucleus assay of bone marrow,sperm abnormality test and genetic toxicity test were negative.No apaprent toxicity was shown by the 30 days-feeding test.Conclusion The Tibetan drug Wangla can be orally comsumped.