碰撞癌的临床影像学表现及病理分析

目的:探讨碰撞癌的临床影像学表现、发病机制与病理特点。方法:回顾性分析20例碰撞癌的临床影像学资料并结合文献复习,总结其患病率、发病年龄、性别比、好发部位、临床影像学表现、治疗手段、病理特点。结果:碰撞癌罕见,好发年龄大于58岁,男性发病多见,好发部位为食管-贲门,食管-胃底等。临床表现无特殊,术前影像学检查多不能明确诊断,术后病理诊断是唯一的确诊方法。治疗以手术为主,辅以化疗或放疗。病理特点为同一宿主同一部位或器官2个不同类型肿瘤的结合,瘤组织间没有移行和混合,有各自的转移途径,碰撞癌以鳞癌和腺癌的碰撞为主。结论:碰撞癌是一种罕见的恶性肿瘤结合,临床特点有待进一步总结,影像学综合诊断有助于提高其确诊率。

The imaging manifestation and pathological analysis of collision carcinoma

Objective:To study the image,pathogenesis and pathological features of collision carcinoma.Methods: Twenty patients were studied retrospectively against the background of literature,including the incidence,age of onset,sex ratio,predilection sites,clinical signs,image apperence,therapy and pathological features.Results: Collision carcinoma was rare,but more common in males than in females.The peak onset age was more than 58 years.It was found frequently in the esophagus-cardiac part,esophagus-fundus of stomach. Absence of special clinical features,it was difficult to diagnose by image inspection before operation.Pathological findings was the only way to make a correct diagnosis.Operation was the major therapy, assisted by chemotherapy and radiotherapy when necessary.Collision carcinoma represented a coexistence of two different malignant neoplasia in an organ.Collision carcinoma was mostly composed of squamous cell carcinoma and adenocarcinoma.Conclusion: Collision carcinoma is rare composed mosaic of malignant tumors.The clinical features of collision carcinoma need further investigatiing,image findings is helpful to increase the rate of correct diagnosis.