住院患者双重及多重耐药菌感染的调查 FREE

目的调查住院患者双重及多重耐药菌感染的情况，提出控制措施。方法对某院2007年1月-2008年12月住院的双重及多重耐药菌感染患者病历进行回顾性调查分析。结果55 084例患者中，有1 436例(2.61%)查出有双重及多重耐药菌感染，其中社区获得性959例（1.74%），医院获得性477例（0.87%），两者之差异有显著性（χ2=323.571，P=0.000）。发生双重及多重耐药菌医院感染者占医院感染总人数的25.74%（1 853例），出现较多的科室是重症监护室(16.98%)、神经外科（14.67%）、烧伤外科（14.25%）、神经内科（14.04%）。感染部位以呼吸道为主（824例次，51.92%）。75.97%（1 091例）的双重及多重耐药菌感染者在感染前使用过抗菌药物。结论双重及多重耐药菌感染以社区获得较多。合理使用抗菌药物是控制和减少双重及多重耐药菌感染的主要措施。

Infections with double and multiple drug resistant bacteria in hospitalized patients FREE

Objective To investigate infections with double and multiple drug-resistant bacteria in hospitalized pa- tients, and to put forward control measures. Methods Medical histry of patients who were hospitalized between January, 2007 and December, 2008 were analysed retrospectively. Results Among 55 084 patients, 1 436 （2. 61%） developed infections with double and multiple drug-resistant bacteria, 959 （1.74%） of which were community-acquired infections, 477（0.87%） were nosocomial infections, there was significant difference between the two （Х^2 = 323. 571, P = 0. 000）. Infection with double and multiple drug-resistant bacteria accounted for 25.74% （1 853 cases） of patients with nosocomial infection. Infection mainly occurred in patients in intensive care unit （16. 98%）, department of neurosurgery （14. 67%）, burn unit（14. 25%） and department of neurology （14. 04%）. The main infection sites were respiratory tract （824 cases, 51.92%）. 75.97% （1 091 cases） of patients received antimicrobial agents before developing infection. Conclusion Infections with double and multiple bacteria are mainly community-acquired infection. Rational appplication of antimierobial agents are the main strategies for controlling and reducing infection with double and multiple bacteria.