| 381例别嘌醇不良反应分析 |
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| 引用本文： | 黄玉斌.381例别嘌醇不良反应分析[J].中国药物应用与监测,2005,2(1):32-34. |
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| 作者姓名： | 黄玉斌 |
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| 作者单位： | 广西壮族自治区第二人民医院,桂林,541002 |
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| 摘 要： | 目的:对别嘌醇引起的381例不良反应进行分析.方法:收集有关别嘌醇不良反应的文献,总结归纳别嘌醇引起的不良反应.结果:381例别嘌醇不良反应中,死亡42例(占11.02%),死亡率高,应引起注意.最常见的不良反应为皮肤-粘膜反应,共369例(占96.85%),其主要表现为药疹.其次是发热,肝、肾功能损害、血液系统损害等不良反应.结论:临床上使用该药时应加强药品不良反应监测.
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| 关 键 词： | 别嘌醇 不良反应 |
| 文章编号： | 1672-8157(2005)01-0032-03 |
| 修稿时间： | 2004年11月9日 |
Analysis of adverse reactions caused by allopurinol in 381 cases |
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| Authors: | HUANG Yu-bin |
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| Abstract: | Objetive:To review adverse reactions related to allopurinol.Methods:Collecting and analysis the adverse reactions of allopurinol.Results:The dead rate of allopurinol was 11.02%,and the most frequent adverse reactions of allopurinol were mucocutaneous whose occurance rate were 96.85%,and the adverse effects of allopurinol were maily rash,follwed by fever,hepatic and renal function abnormal.Conclusion:It is very important to enhance ADR monitoring in their cliniccal use. |
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| Keywords: | Allopurinol:Adverse reactions |
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