机械振动的成骨效应研究进展

应力是骨形成的“指导性”因素。其机制是近十年来骨科学、生物医学工程及康复医学领域的研究热点。机械振动是力学刺激形式之一。诸多研究表明：振动具有显著的成骨效应,其在骨质疏松的治疗中将会有广阔的应用前景。但是,现有相关研究中,具有成骨效应的振动频率、强度等参数并不一致,尤其是振动的成骨机制不明,相关报道极少,本文对其作一论述,可为更系统、深入地研究及其在临床中的应用提供理论基础。

Osteogenetic effect of mechanical vibration on bone

Mechanical loading is the main ＂instructive＂ factor of bone formation. The mechanism becomes the heat point in the field of bone science, biomedicine project and rehabilitation research, Mechanical vibration is one of the mechanic stimulation. Evidences show that vibration has obvious anabolic effect,and will have a broad landscape in the treatment of osteoporosis. But in the present studies, there were incorporated with the vibration frequency, and intensity, in particularly ,few reports about the mechanism of vibration to bone. It will provide theoretic foundation for further systematic, sound research and its clinical application.