广州市诺如病毒感染性胃肠炎疾病负担评估

目的 对广州市诺如病毒感染性胃肠炎的疾病负担进行评估，为政府制定传染性胃肠炎和食源性疾病管理决策和控制措施提供科学依据。方法 分别评估广州市诺如病毒感染性胃肠炎散发和暴发部分的疾病负担，评估指标包括伤残调整生命年、发病率、住院率、罹患率等，数据主要来源于监测医院、历史文献资料以及“突发公共卫生事件管理信息系统”中的相关数据。结果 2014年广州市腹泻总病例数约为3 092 230人次，其中由诺如病毒感染所引起的腹泻病例数约为608 860人次。广州市2014年诺如病毒感染性胃肠炎年发病率为4 655/10万，住院率为0.03%，共发生暴发疫情6起，病例942例，平均罹患率为2.63%。综合散发与暴发数据，广州市2014年诺如病毒感染性胃肠炎的疾病负担为2 212 DALYs。结论 广州市诺如病毒感染性胃肠炎疾病负担较高，相关卫生部门应重视并加强对诺如病毒感染性胃肠炎的预防、控制管理以及教育宣传，开展针对性防控。

The estimated disease burden of norovirus gastroenteritis in Guangzhou

Objective This study aims to estimate the disease burden of norovirus gastroenteritis in Guangzhou in 2014, and provide scientific evidence for the government's decision-making and control measures for infectious gastroenteritis and foodborne diseases. Methods The study was conducted by separately estimating the disease burden of both the outbreak and sporadic situations of norovirus gastroenteritis in Guangzhou. The indicators include disability-adjusted life years, morbidity, hospitalisation rate and morbidity. Data was acquired from monitoring hospitals, other research literature and the "public health emergency management information system". Results The total number of diarrhoea cases was approximately 3 092 230 in Guangzhou in 2014, of which 608 860 cases were related to a norovirus infection. The annual incidence of norovirus gastroenteritis was 4 655/100 000 people, with a hospitalisation rate of 0.03%. There were also six cases of outbreaks in Guangzhou in 2014, with an average prevalence of 2.63%. Integrating the data from sporadic and outbreak situations, the estimated disease burden of norovirus gastroenteritis in Guangzhou in 2014 was 2 212 DALYs. Conclusions The disease burden of norovirus gastroenteritis in Guangzhou is high, indicating that relevant health departments should strengthen their prevention, control and management efforts for norovirus gastroenteritis infections, in addition to increasing education and awareness.