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Emerging Viral Infections Causing Anterior Uveitis
Authors:Moncef Khairallah  Padmamalini Mahendradas  Andre Curi  Sana Khochtali  Emmett T Cunningham Jr
Affiliation:1. Department of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine, University of Monastir, Monastir, Tunisiamoncef.khairallah@yahoo.fr;3. Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, India;4. Research Laboratory of Infectious Diseases in Ophthalmology, National Institute of Infectious Diseases, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil;5. Department of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine, University of Monastir, Monastir, Tunisia;6. Department of Ophthalmology, California Pacific Medical Center, San Francisco, CA, USA;7. Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA, USA;8. UCSF School of Medicine, The Francis I. Proctor Foundation, San Francisco, CA, USA
Abstract:Purpose: To review the systemic and ocular manifestations of specific emergent viral infectious diseases relevant to the ophthalmologist with particular emphasis on anterior uveitis

Methods: Review of literature.

Results: Arboviral diseases are among the most important emergent and resurgent human infections, occurring mostly in tropical and subtropical zones, but appearing in virtually all regions of the world as a result of climate change, travel, and globalization. Arboviral infections are transmitted to humans by the bite of hematophagous arthropods, mainly mosquitoes. Systemic disease may range from asymptomatic to life-threatening. A wide variety of ocular manifestations, including uveitis, has been reported in association with these emerging viral diseases. Numerous viruses other than arboviruses also have been recently recognized as a potential cause of uveitis.

Conclusions: Proper clinical diagnosis of any emerging infectious disease is based on epidemiological data, history, systemic symptoms and signs, and the pattern of ocular involvement. The diagnosis is usually confirmed by detection of virus-specific DNA or antivirus antibodies in serum.
Keywords:Arbovirus infection  anterior  uveitis  viral ocular infection  viruses
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