超声引导下经皮微波消融与CT超声引导下肿瘤射频消融治疗原发性肝癌的临床比较

目的探讨超声引导下经皮微波消融与CT超声引导下肿瘤射频消融治疗原发性肝癌的临床比较。方法选取2009年2月-2013年3月我院微创介入治疗科收治的46例(72个病灶)原发性肝癌患者为研究对象,随机数字表法均分为研究组和对照组,对照组行超声引导下经皮微波消融治疗,研究组行CT超声引导下肿瘤射频消融治疗,观察两组围术期相关指标手术时间、术后住院时间、住院费用],消融情况消融点数、消融时间]、临床疗效影像学评价、3年随访复发率。结果研究组手术时间、术后住院时间分别均较对照组显著短(P0.05),两组住院费用相较无显著差异(P0.05);两组术后病灶均较好地清除;研究组3年复发率较对照组显著低,差异具有统计学意义(χ2=5.254,P0.05)。结论超声引导下经皮微波消融与CT超声引导下肿瘤射频消融对原发性肝癌的临床疗效均显著,射频消融在手术时间、住院时间、消融时间、3年复发率方面均具有更显著优势,值得临床推广应用。

Clinical Comparison of Ultrasound-guided Percutaneous Microwave Ablation and CT Ultrasound-guided Radiofrequency Ablation in Treating Primary Liver Cancer

Objective Tocompare the effects between ultrasound-guided percutaneous microwave ablation and CT ultrasound-guided radiofrequency ablation in treating primary liver cancer. Methods Forty-six patients (72 lesions) with primary liver cancer treated by minimal invasive interventional therapy in our hospital between February 2009 and March 2013 were selected as study subjects and were equally divided into study group and control group by the random number table method. The control group received ultrasound-guided percutaneous microwave ablation while study group received CT ultrasound-guided radiofrequency ablation. The related perioperative indexes (operation time, postoperative length of stay, hospitalization expenses), state of ablation (ablation count, duration of ablation), imaging evaluation of clinical efficacy, 3 year follow-up recurrence rate in the two groups were observed. Results Operation time and postoperative length of stay of study group were significantly shorter than control group (P<0.05). There was no significant difference in hospitalization expenses between the two groups (P>0.05), after operation, lesions in both groups were effectively removed. The 3-year recurrence rate in study group was significantly lower than control group (χ2=5.254, P<0.05). Conclusion Clinical efficacy of both ultrasound-guided percutaneous microwave ablation and CT ultrasound-guided radiofrequency ablation are significant in treating primary liver cancer. Radiofrequency ablation has more advantages in operation time, length of stay, duration of ablation and 3-year recurrence rate.