血脂异常与老年冠心病患者冠脉病变程度的相关性研究

目的 探讨血脂异常与老年冠心病患者冠脉病变程度的相关性。方法 选取2015年5月~2017年1月本院心内科住院的明确诊断为冠状动脉粥样硬化性心脏病（CHD）的150例老年患者设为CHD组。选取同期收治的150例非CHD患者为对照组。比较两组血清中总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）水平，并计算N-HDL-C、LDL-C/N-HDL-C、LDL-C/HDL-C、TC/HDL-C、TG/HDL-C值。比较不同冠脉病变支数、不同病情严重程度的CHD患者的血脂及其比值。对血脂与冠脉病变支数、病情严重程度积分进行相关性分析。结果 CHD组患者LDL-C、TG、TC、N-HDL-C水平、LDL-C/HDL-C、TC/HDL-C、TG/HDL-C值均高于对照组，HDL-C水平低于对照组，差异均有统计学意义（P＜0.05）；不同冠脉病变支数各亚组间的TC、TG、N-HDL-C水平、TC/HDL-C比值差异存在统计学意义（P＜0.05）；TC、TG、N-HDL-C水平、TC/HDL-C比值均与冠脉病变支数均呈正相关（P＜0.05）；不同病情严重程度亚组间的LDL-C、TC、TG、N-HDL-C水平、LDL-C/HDL-C、TC/HDL-C、TG/HDL-C比值差异存在统计学意义（P＜0.05）；CHD患者LDL-C、TC、TG、N-HDL-C水平、LDL-C/HDL-C、TC/HDL-C、TG/HDL-C比值与冠状动脉病变积分均呈正相关（P＜0.05）。结论 可以通过对血脂指标的监测，并计算N-HDL-C、TC/HDL-C、LDL-C/HDL-C、TC/HDL-C、TG/HDL-C值，来评估CHD病情的临床进展。

Correlation Study between Dyslipidemia and Degree of Coronary Artery Disease in Elderly Patients with Coronary Heart Disease

Objective To investigate the relationship between dyslipidemia and the severity of coronary artery disease in elderly patients with coronary heart disease.Methods A total of 150 elderly patients with coronary atherosclerotic heart disease (CHD) who were diagnosed with coronary heart disease (CHD) from May 2015 to January 2017 were enrolled in the CHD group. 150 non-CHD patients were enrolled in the same period. For the control group. The levels of total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) in serum were compared between the two groups, and N-HDL-C and LDL were calculated. -C/N-HDL-C, LDL-C/HDL-C, TC/HDL-C, TG/HDL-C values. Compare the blood lipids and their ratios of CHD patients with different coronary lesions and severity of different diseases. Correlation analysis was performed on the scores of blood lipids and coronary lesions and the severity of the disease.Results The levels of LDL-C, TG, TC, N-HDL-C, LDL-C/HDL-C, TC/HDL-C, TG/HDL-C in the CHD group were higher than those in the control group, and the HDL-C level was low. In the control group, the difference was statistically significant (P<0.05); there were statistically significant differences in TC, TG, N-HDL-C levels, and TC/HDL-C ratios among the subgroups of different coronary lesions (P<0.05); TC, TG, N-HDL-C level, TC/HDL-C ratio were positively correlated with coronary artery lesions (P<0.05); LDL-C between subgroups of different severity of disease TC, TG, N-HDL-C levels, LDL-C/HDL-C, TC/HDL-C, TG/HDL-C ratios were statistically significant (P<0.05); CHD patients with LDL-C, TC, TG, N-HDL-C level, LDL-C/HDL-C, TC/HDL-C, TG/HDL-C ratio were positively correlated with coronary artery lesion scores (P<0.05). Conclusion The clinical evaluation of CHD can be evaluated by monitoring the blood lipid index and calculating N-HDL-C, TC/HDL-C, LDL-C/HDL-C, TC/HDL-C, and TG/HDL-C values. progress.