| 发光细菌对化合物的致突效应与检测研究 |
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| 引用本文： | 顾宗濂,谢思琴,周德智.发光细菌对化合物的致突效应与检测研究[J].环境科学学报,1993,13(4):435-441. |
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| 作者姓名： | 顾宗濂 谢思琴 周德智 |
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| 作者单位： | 中国科学院南京土壤研究所 210008
(顾宗濂，谢思琴)，中国科学院南京土壤研究所 210008(周德智) |
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| 摘 要： | 从明亮发光杆菌Ｔ３小种分离到的自发暗变种（Ｋ变种）Ｔ９１７１菌种对三种化合物呈致空变阳性反应，对二种化合物呈可疑阳性，发光细菌暗变种对遗传毒性化合物致突效应的灵敏度高于Ａｍｅｓ试验和浦乳动物致癌试验，可望成为一种简易灵敏的测试环境致突变物的短期生物学试验方法。
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| 关 键 词： | 发光细菌 暗变种 致突变性 化合物 |
| 收稿时间： | 1992/2/10 0:00:00 |
RESPONSE OF PHOTOBACTERIA TO CHEMICALS' MUTAGENICITY AND ITS DETECTION |
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| Gu Zonglian,Xie Siqin and Zhou Dezhi.RESPONSE OF PHOTOBACTERIA TO CHEMICALS'' MUTAGENICITY AND ITS DETECTION[J].Acta Scientiae Circumstantiae,1993,13(4):435-441. |
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| Authors: | Gu Zonglian Xie Siqin and Zhou Dezhi |
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| Affiliation: | Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008,Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008 and Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008 |
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| Abstract: | The positive mutagenic response to four chemicals and doubtable positive mutagenic response to one chemical were demonstrated by a spontaneous dark mutant (K mutant), strain T9171, isolated from Photobacterium phosphoreum T3 spp. Mutagenic response of the Photobacteria' s dark mutant has higher sensitivity to genotoxic chemicals as compared with mutagenic test of Salmo-nella/microsome (Ames test) and carcinogenic test of mammal. |
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| Keywords: | dark mutant mutagenic effect photobacteria |
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