| 国产重组链激酶与进口重组组织型纤溶酶原激活剂静脉溶栓治疗急性心肌梗塞的临床对比观察 |
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| 引用本文： | 杜爱英,任礼静,高红梅.国产重组链激酶与进口重组组织型纤溶酶原激活剂静脉溶栓治疗急性心肌梗塞的临床对比观察[J].河北医学,1999(7). |
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| 作者姓名： | 杜爱英 任礼静 高红梅 |
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| 作者单位： | 山西省阳泉市第一人民医院 |
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| 摘 要： | 目的：比较重组链激酶（ｒ－ｓｋ）与重组组织型纤溶酶原激活剂（ｒｔ－ＰＡ）静脉溶栓对急性心肌梗塞的效果与其副作用；方法：急性心肌梗塞患者发病６ｈ内者２６例给予静脉ｒｔ－ＰＡ，另２７例给予静脉内ｒ－ｓｋ溶栓；结果：ｒｔ－ＰＡ组、ｒ－ｓｋ组临床血管再通率分别为８４．６％与７７．３％（Ｐ＞０．０５），前者局部出血并发症为１１．５％，呼吸道出血为７．７％，后者分别为３．７％与０（Ｐ＞０．０５）；结论：静脉ｒ－ｓｋ溶栓血管再通率及出血并发症与ｒｔ－ＰＡ无明显差异。
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| 关 键 词： | 重组链激酶 重组组织型纤溶酶原激活剂 静脉溶栓 急性心肌梗塞 |
THECLINICALCOMPARISIONOFINTRAVENOUS THROMBOLYTIC THERAPYWITHDOMESTIC RECOMBINANTSTREPTOKINASE ANDFOREIGN RECOMBINANTTISSUETYPE PLASMINOGEN ACTIVATORINPATIENTS WITHACUTE MYOCARDIALINFARCTION |
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| DuAiying,RenLijing,GaoHongmei.THECLINICALCOMPARISIONOFINTRAVENOUS THROMBOLYTIC THERAPYWITHDOMESTIC RECOMBINANTSTREPTOKINASE ANDFOREIGN RECOMBINANTTISSUETYPE PLASMINOGEN ACTIVATORINPATIENTS WITHACUTE MYOCARDIALINFARCTION[J].Hebei Medicine,1999(7). |
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| Authors: | DuAiying RenLijing GaoHongmei |
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| Abstract: | Objective:T5,5BZTocomparetheeffectivenessandcomplicationsofintravenousrecombinantstreptokinase(rsk)andrecombinanttissuetypeplasminogenactivator(rtPA)inpatientswithacutemyocardialinfarction(AMI). Methods: 26patientsinrtPAgroupand27patientsinrskgroupwereincludedinthestudy,andeitherofthemweresimultaneouslytreatedwithintravenousrskrtPA. Results: TheclinicalreperfusionratesinrtPAandrskgroupwere84.6%and77.3%(P>0.05),respectively.WhileinrtPAgroupthepartialbleedingcomplicationratewas11.5%.respiratorybleedingratewas7.7%.Inrskgroupwere3.7%and0(P>0.05),respectively. Conclusion:5BZThepatientswithAMItreatedwithintravenousrskrtPAwithin6hoursafteronsetofsymptomshadntobviousdifferenceofreperfusionratesandhemorrhagiccomplications. |
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| Keywords: | Recombinantstreptokinase Recombinanttissuetypeplasminogenactivator Intravenousthrombolytictherapy Acutemyocardialinfarction |
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