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大气颗粒物急性健康效应的Meta分析方法及R软件实现
引用本文:李亚伟,郭默宁,李成橙,陈晨,路凤.大气颗粒物急性健康效应的Meta分析方法及R软件实现[J].卫生研究,2019(2):312-319.
作者姓名:李亚伟  郭默宁  李成橙  陈晨  路凤
作者单位:中国疾病预防控制中心环境与健康相关产品安全所;北京市卫生计生委信息中心北京市卫生计生委政策研究中心
摘    要:目的介绍大气颗粒物急性健康效应的Meta分析和利用R软件实现的方法。方法以文献数据库"1990至2013年PM10对普通中国人群呼吸系统死亡影响"为例,进行Meta分析,并用R软件实现。结果示例数据库存在一定发表偏倚,合并RR值为1.0041(95%CI 1.0028~1.0054),利用剪补法调整后RR值为1.0015(95%CI 1.0002~1.0029)。结论 R软件可以方便实现大气颗粒物急性健康效应的Meta分析。

关 键 词:META分析  大气颗粒物  急性健康效应  R软件

Meta-analysis of acute health effects caused by atmospheric particulate matter and the implementation with R software
Li Yawei,Guo Moning,Li Chengcheng,Chen Chen,Lu Feng.Meta-analysis of acute health effects caused by atmospheric particulate matter and the implementation with R software[J].Journal of Hygiene Research,2019(2):312-319.
Authors:Li Yawei  Guo Moning  Li Chengcheng  Chen Chen  Lu Feng
Affiliation:(National Institute of Environmental Health,China CDC,Beijing 100021,China;Beijing Municipal Commission of Health and Family Planning Information Center,Beijing Municipal Commission of Health and Family Planning Policy Research Center,Beijing 100034,China)
Abstract:OBJECTIVE To introduce the Meta-analysis of acute health effects caused by atmospheric particulate matter and explore the R software implementation.METHODS Used literature data as an example,pooled the risk estimates of mortality due to respiratory disease exposure to PMI0 in the Chinese population from 1990 to 2013 using R software.RESULTS The overall risk estimates RR was 1.0041(95%CI 1.0028-1.0054),there was publication Bias,the RR was reduced to 1.0015(95%CI 1.0002-1.0029)after adjust the asymmetry with the trim-and-fill method.CONCLUSION R software has relatively abundant software packages to conduct the Meta-analysis for assessing the acute health impact exposure to atmospheric particulate matter.
Keywords:Meta-analysis  atmospheric particulate matter  acute health effects  R software
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