| 卡铂加顺铂治疗晚期非小细胞肺癌的疗效观察 |
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| 引用本文： | 周定.卡铂加顺铂治疗晚期非小细胞肺癌的疗效观察[J].癌症,1994,13(3):245-246. |
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| 作者姓名： | 周定 |
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| 作者单位： | 湖南省肿瘤医院 |
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| 摘 要： | 全组共１９例经病理学证实的晚期非小细胞肺癌。应用卡铂３００ｍｇ／ｍ＾２第１天静脉输入，顺铂２０ｍｇ／ｍ＾２第１－３天静脉输入，每３周重复一次。１９例均可评定疗效与毒性。８例（４２．１％）获部分缓解，无完全缓解病例，其中未接受过化疗的１５例，７例（４６．７％）获部分缓解。毒副反应主要为骨髓抑制。消化道反应等。
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| 关 键 词： | 卡铂 顺铂 肺肿瘤 小细胞癌 |
THERAPEUTIC RESULT OF PHASE II CLINICAL TRIAL OF CISPLATIN PLUS CARBOPLATIN THERAPY IN NON-SMALL CELL LUNG CANCER(NSCLC) |
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| ZHoU Ding.THERAPEUTIC RESULT OF PHASE II CLINICAL TRIAL OF CISPLATIN PLUS CARBOPLATIN THERAPY IN NON-SMALL CELL LUNG CANCER(NSCLC)[J].Chinese Journal of Cancer,1994,13(3):245-246. |
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| Authors: | ZHoU Ding |
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| Abstract: | A phase II pilot study of carboplatin 300mg/m2 followed by cisplatin60mg/m2 was initiated in 19 patients with NSCLC. Interim analysis showed that 8 patentshave had at least a partial response to cisplatin/carboplatin, with a response rate of 42.1%The response rate in previously untreated patients was 46. 7%,while in previously treatedpatients was 25%. No serio us adverse effects were oberved.Futher studies with the cis-platin/carboplatin combination in NSCIC are warranted. |
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| Keywords: | Non-small cell cancer Cisplatin Carbopla tin |
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