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中药红泽兰化学成分的研究
引用本文:黄静,涂茂浰,谢晶曦.中药红泽兰化学成分的研究[J].药学学报,1987,22(4):264-268.
作者姓名:黄静  涂茂浰  谢晶曦
作者单位:华西医科大学药学系 成都 (黄静,涂茂浰),中国医学科学院药物研究所 北京(谢晶曦)
摘    要:本文报道从中药红泽兰(爵床科马兰属植物垂序马兰StrobilanShes japonicusⅠ的全草)中分离出的黄酮和甾醇四种成分。经化学及光谱分析鉴定其中之一为新黄酮甙(Ⅱ),命名为红泽兰甙(strobilanthin),即5,7-二甲氧基-4′-羟基黄酮-4’-0-芹糖甙;另一系首次直接从天然界中分得的黄酮化合物(Ⅰ),为前者的甙元即5,7-二甲氧基-4’-羟基黄酮;其余两种均首次从马兰属植物中分出,分别为豆甾醇(Ⅲ)和豆甾-8(14)-烯-3-醇(Ⅳ)。

关 键 词:红泽兰  5  7-二甲氧基-4’-羟基黄酮  5  7-二甲氧基-4’-羟基黄酮-4’-0-芹糖甙  红泽兰甙  甾醇
收稿时间:1986-05-07

STUDIES ON THE CHEMICAL CONSTITUENTS OF CHINESE HERB HONG-ZE-LAN, STROBILANTHES JAPONICUS (THUNB.) MIQ
HUANG Jing,TU Mao-Li and XIE Jing-Xi.STUDIES ON THE CHEMICAL CONSTITUENTS OF CHINESE HERB HONG-ZE-LAN, STROBILANTHES JAPONICUS (THUNB.) MIQ[J].Acta Pharmaceutica Sinica,1987,22(4):264-268.
Authors:HUANG Jing  TU Mao-Li and XIE Jing-Xi
Affiliation:HUANG Jing,TU Mao-Li and XIE Jing-Xi~*
Abstract:Hong-Ze-Lan is the Chinese name of the whole herb of Strobilanthes japonicus (Thunb.) Miq. (Acanthaceae). It has been used commonly in China as a folk medicine.From "Hong-Ze-Lan", four class of compounds (flavones, sterols, alkanes and inorganic salts) were isolated and identified by spectroscopic and chemical methods. In this paper we report the identification of four constituents including two flavones and two sterols. A new flavone glycoside (Ⅱ), named strobilanthin, was comfirmed to be 5,7-dimethoxy-4'-hydroxyflavone-4'-O-apioside. Another flavone (Ⅰ) was identified as 5,7-dimethoxy-4'-hydroxyflavone. The two sterols were identified as stigmasterol (Ⅲ) and stigmast-8(14)-en-3-ol (Ⅳ).
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