| 银杏叶提取物速释滴丸的研制 |
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| 引用本文： | 葛月宾,陈大为,李智博,马燕,宋华先,胡海洋.银杏叶提取物速释滴丸的研制[J].中国中药杂志,2003,28(5):410-413. |
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| 作者姓名： | 葛月宾 陈大为 李智博 马燕 宋华先 胡海洋 |
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| 作者单位： | 沈阳药科大学,药学院,辽宁,沈阳,110016 |
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| 摘 要： | 目的 :研究银杏叶提取物速释滴丸的处方和滴制工艺。方法 :分别以银杏总黄酮溶出百分量和丸重差异为评价指标 ,采用正交试验进行处方和工艺优化。结果 :优化结果表明 ,滴丸平均T50 为 3.62min ,平均丸重差异为2.80%。结论 :所研制的银杏叶提取物速释滴丸能明显提高有效成分的溶出速率 ,达到制剂目的。
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| 关 键 词： | 银杏叶提取物 速释滴丸 正交设计 |
| 文章编号： | 1001-5302(2003)05-0410-04 |
| 收稿时间： | 2003/1/10 0:00:00 |
| 修稿时间： | 2003年1月10日 |
Study on the Preparation of Rapid-dissoluted EGb Droppills |
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| GE Yue bin;CHEN Da wei;LI Zhi bo;MA Yan;SONG Hua xian;HU Hai yang.Study on the Preparation of Rapid-dissoluted EGb Droppills[J].China Journal of Chinese Materia Medica,2003,28(5):410-413. |
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| Authors: | GE Yue bin;CHEN Da wei;LI Zhi bo;MA Yan;SONG Hua xian;HU Hai yang |
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| Affiliation: | School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, Liaojing, China. |
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| Abstract: | Objective: To study the formulation and technique of preparation of rapid dissoluted EGb (Extract of Ginkgo biloba) droppills. Method: Taking the dissolution percentage of total flavonoids in EGb and weight variation as index, the formulation and technique of EGb droppills were optimized by the orthogonal experiment. Result: T 50 was 3.62 min and mean weight variation was 2.80%. Conclusion: Rapid dissoluted EGb droppills can increase the dissoluting rate distinctly and reach the purpose of preparation. |
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| Keywords: | Extract of Ginkgo biloba (EGb) droppills orthogonal experiment |
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