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凝血弹性图在活体肝移植术中应用的研究
引用本文:王清平,杜洪印,石屹崴,刘伟华,强喆.凝血弹性图在活体肝移植术中应用的研究[J].疑难病杂志,2011,10(9):667-669.
作者姓名:王清平  杜洪印  石屹崴  刘伟华  强喆
作者单位:天津市第一中心医院麻醉科,300192
摘    要:目的对成人活体肝移植术中使用凝血弹性图进行凝血功能监测,探讨手术各阶段凝血紊乱的诱因及相应治疗方法。方法 33例行活体肝移植手术患者,于手术开始时(T_1)、无肝期再灌注前5min(T_2)、新肝期再灌注后5min(T_3)及再灌注后60min(T_4)进行肝素酶修正及自然全血凝血弹性图检测。结果 T_1及T_2肝素酶修正组与自然全血组凝血弹性图数值差异无统计学意义(P>0.05)。T_3时自然全血组与肝素酶修正组数据均显示低凝状态且肝素或肝素样物质为主要原因。T_4后肝素造成的凝血异常逐步改善,但较之T_1仍处于低凝状态。结论凝血弹性图对凝血状况的连续监测可以快速准确判断活体肝移植术中不同阶段凝血异常的原因,指导临床针对性治疗,并可评价治疗效果。

关 键 词:凝血弹性图  凝血功能  活体肝移植

Investigation of thromboelastography in the peri-operative period of living donor liver transplantation
WANG Qing-ping,DU Hong-yin,SHI Yi-wei,et al..Investigation of thromboelastography in the peri-operative period of living donor liver transplantation[J].Journal of Difficult and Complicated Cases,2011,10(9):667-669.
Authors:WANG Qing-ping  DU Hong-yin  SHI Yi-wei  
Affiliation:WANG Qing-ping,DU Hong-yin,SHI Yi-wei,et al.Department of Anesthesiology,Tianjin First Central Hospital,Tianjin 300192,China
Abstract:Objective To monitor the efficiency of coagulation in the blood using peri-operative thromboelastography, to investigate the causes of coagulopathy and find out the best treatment methods in patients with living donor liver transplantation. Methods Data were collected from 33 patients with living donor liver transplantation.The coagulation profile was evaluated by heparanase modified TEG(HTEG) and the native TEG(NTEG) at the beginning of surgery(T_1),5 min before reperfusion(T_2),5 min after reperfusion(T_3...
Keywords:Thrombelastography  Coagulation  Living donor liver transplantation  
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