腹腔热灌注化疗对恶性腹水的疗效观察

目的研究腹腔热灌注化疗对恶性腹水的疗效。方法40例患者随机分为治疗组与对照组,治疗组患者21例,接受腹腔热灌注化疗并内生场热疗,对照组患者19例,接受常温的腹腔灌注化疗。结果腹腔热灌注化疗组完全缓解(CR)6例,部分缓解(PR)10例,平均缓解期5个月,常温腹腔灌注化疗组CR 0例,PR 7例,平均缓解期1个月。两组相比差异有显著意义。腹痛发生率热灌注化疗组2例,常温灌注化疗组1例,两组相比差异无显著意义。结论腹腔热灌注化疗可以明显提高恶性腹水患者的治疗疗效,并不增加其副作用。

Clinical investigation of chemotherapy with intraperitoneal hyperthermal perfusion for malignant ascites

Objective To observe the clinical effects of chemotherapy with intraperitoneal hyper-thermal perfusion for malignant ascites. Methods 40 patients with malignant ascites were randomly divided into two groups. In the treated group, 21 patients underwent intraperitoneal hyperthermal perfusion and local thermotherapy. 19 patients in the control group received commonly intraperitoneal perfusion. Results The CR, PR patients were 6,10 and 0,7 in the treated group and control group, respectively. The efficacy rate in the treated group was significantly higher than that in the control group. 2 patients oc-cured bellyache in the treated group and 1 patient in the control group, there was no statistically significant difference between the two groups. Conclusion Chemotherapy with intraperitoneal hyperthermal perfusion can significantly improve the therapeutic effects for malignant ascites, and has no more side effects.