| 复方甘草酸苷联合还原型谷胱甘肽治疗抗结核药所致肝损害的临床疗效分析 |
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| 引用本文： | 林跃平.复方甘草酸苷联合还原型谷胱甘肽治疗抗结核药所致肝损害的临床疗效分析[J].现代医药卫生,2011,27(9):1308-1309. |
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| 作者姓名： | 林跃平 |
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| 作者单位： | 遂宁市船山区疾病预防中心,四川,遂宁,629000 |
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| 摘 要： | 目的:观察复方甘草酸苷联合还原型谷胱甘肽治疗抗结核药所致肝损害的临床疗效.方法:将69例抗结核药引起的药物性肝炎患者随机分成观察组37例和对照组32例,观察组给予复方甘草酸苷联合还原型符胱甘肽治疗4周,对照组给予还原型谷胱甘肽治疗4周,观察两组患者治疗前后肝功能指标情况、治疗总有效率及药物不良作用.结果:观察组患者的肝功能指标改善情况优于对照组(P<0.05,P<0.01),观察组与对照组总有效率分别为91.9%和71.9%(P<0.05),未见药物不良反应.结论:复方甘草酸苷联合还原型谷胱甘肽对于抗结核药引起的药物性肝炎具有较好的降酶保肝作用.
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| 关 键 词： | 药物性肝炎 抗结核药 复方甘草酸苷 还原型谷光甘肽 |
Treatment efficacy of liver damage caused by antituberculosis drugs with compound glycyrrhizin and reduced glutathione |
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| LIN Yue-ping.Treatment efficacy of liver damage caused by antituberculosis drugs with compound glycyrrhizin and reduced glutathione[J].Modern Medicine Health,2011,27(9):1308-1309. |
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| Authors: | LIN Yue-ping |
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| Affiliation: | LIN Yue-ping(Chuanshan District Center for Disease Control and Prevention,Suining,Sichuan 629000,China) |
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| Abstract: | Objective:To investigate the treatment efficacy of liver damage caused by antituberculosis drugs with compound glycyrrhizin and reduced glutathione.Methods:69 patients of anti-TB drug-induced hepatitis were randomly divided into control group(32 cases) and observation group(37 cases).In the observation group,compound glycyrrhizin and reduced glutathione were given for 4 weeks,while in the control group,reduced glutathione was given for 4 weeks.Liver function before and after treatment,treatment efficacy and... |
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| Keywords: | Drug-induced hepatitis Anti-TB drugs Compound glutathione Reduced glycyrrhizin |
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